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Polypoid melanoma

Polypoid melanoma
Polypoid melanoma of the left ear in 83-year old woman.
SpecialtyDermatology/Oncology

Polypoid melanoma is a rare cutaneous condition, a virulent variant of nodular melanoma.[1]: 696  Polypoid melanoma is a subtype of nodular melanoma, the most aggressive form of melanoma (a skin cancer).[2]

Signs and symptoms

Polypoid melanoma is distinguished by a profile that resembles cauliflower and an uneven surface.[3]

Treatment

Therapies for metastatic melanoma include the biological immunotherapy agents ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib; and an MEK inhibitor trametinib.[4]

See also

References

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
  2. ^ Maury, Mikalah E; Jukic, Drazen M (October 13, 2023). "A Case Presentation of Three Polypoid Melanomas With Divergent Features". Cureus. 15 (10). Springer Science and Business Media LLC: e46951. doi:10.7759/cureus.46951. ISSN 2168-8184. PMC 10640706. PMID 38022238.
  3. ^ Di Altobrando, Ambra; Patrizi, Annalisa; Dika, Emi; Savoia, Francesco (2020). "Cauliflower-like exophytic mass on the skin: polypoid melanoma. Clinical, dermoscopic, and histologic features". Anais Brasileiros de Dermatologia. 95 (6). Elsevier BV: 748–750. doi:10.1016/j.abd.2020.04.010. ISSN 0365-0596. PMC 7672400. PMID 33041156.
  4. ^ Maverakis E, Cornelius LA, Bowen GM, Phan T, Patel FB, Fitzmaurice S, He Y, Burrall B, Duong C, Kloxin AM, Sultani H, Wilken R, Martinez SR, Patel F (2015). "Metastatic melanoma — a review of current and future treatment options". Acta Derm Venereol. 95 (5): 516–524. doi:10.2340/00015555-2035. PMID 25520039.

Further reading
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