RGC100
RGC100 is an immune stimulant drug. It is a double-stranded RNA molecule of 100 G:C base pairs, with a molecular weight of 64.9 KDa. It activates dendritic cells of the human immune system by specifically targeting endosomal TLR3, while mostly avoiding MDA5. It has good solubility and serum stability.[1]
References
- ^ Naumann, Kai; Wehner, Rebekka; Schwarze, Anett; Petzold, Christiane; Schmitz, Marc; Rohayem, Jacques (2013). "Activation of Dendritic Cells by the Novel Toll-Like Receptor 3 Agonist RGC100". Clinical and Developmental Immunology. 2013 283649. doi:10.1155/2013/283649. PMC 3878805. PMID 24454470.
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