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RNF13
Identifiers
Aliases	RNF13, RZF, ring finger protein 13, EIEE73, DEE73
External IDs	OMIM: 609247; MGI: 1346341; GeneCards: RNF13
Enzyme activity
Gene location (Human)
Chr.	Chromosome 3 (human)
End	149,962,139 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	57,742,654 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; Achilles tendon; ; inferior ganglion of vagus nerve; ; C1 segment; ; subthalamic nucleus; ; parotid gland; ; optic nerve; ; retinal pigment epithelium; ; external globus pallidus; ; pars reticulata;
	Top expressed in
	retinal pigment epithelium; ; deep cerebellar nuclei; ; sciatic nerve; ; globus pallidus; ; iris; ; pontine nuclei; ; lateral geniculate nucleus; ; ventral tegmental area; ; ciliary body; ; stroma of bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; transferase activity; zinc ion binding;
Cellular component	integral component of membrane; lysosomal membrane; Golgi membrane; nuclear inner membrane; endosome; lysosome; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; late endosome membrane; nucleus; membrane; nucleoplasm; cytosol; intracellular membrane-bounded organelle;
Biological process	protein ubiquitination; protein autoubiquitination; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	11342
	24017
	ENSG00000082996
	ENSMUSG00000036503
	O43567
	O54965
NM_007282; NM_183381; NM_183382; NM_183383; NM_183384;
	NM_001378285; NM_001378286; NM_001378287; NM_001378288; NM_001378289; NM_001378290; NM_001378291
	NM_001113413; NM_011883; NM_001304454; NM_001304456; NM_001357080
NP_009213; NP_899237; NP_899239; NP_001365214; NP_001365215;
	NP_001365216; NP_001365217; NP_001365218; NP_001365219; NP_001365220
	NP_001106884; NP_001291383; NP_001291385; NP_036013; NP_001344009
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein 13 is a protein that in humans is encoded by the RNF13 gene.^[5]

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. The specific function of this gene has not yet been determined. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000082996 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036503 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: RNF13 ring finger protein 13".

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Wesselkamper SC, McDowell SA, Medvedovic M, et al. (2006). "The role of metallothionein in the pathogenesis of acute lung injury". Am. J. Respir. Cell Mol. Biol. 34 (1): 73–82. doi:10.1165/rcmb.2005-0248OC. PMC 2644192. PMID 16166738.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Tranque P, Crossin KL, Cirelli C, et al. (1996). "Identification and characterization of a RING zinc finger gene (C-RZF) expressed in chicken embryo cells". Proc. Natl. Acad. Sci. U.S.A. 93 (7): 3105–9. Bibcode:1996PNAS...93.3105T. doi:10.1073/pnas.93.7.3105. PMC 39769. PMID 8610176.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000082996 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036503 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: RNF13 ring finger protein 13".

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RNF13

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