SYTL1

SYTL1
Identifiers
AliasesSYTL1, JFC1, SLP1, synaptotagmin like 1
External IDsOMIM: 608042; MGI: 1933365; GeneCards: SYTL1
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

84958

269589

Ensembl

ENSG00000142765

ENSMUSG00000028860

UniProt

Q8IYJ3

Q99N80

RefSeq (mRNA)

NM_001193308
NM_032872

NM_031393

RefSeq (protein)

NP_001180237
NP_116261

n/a

Location (UCSC)Chr 1: 27.34 – 27.35 MbChr 4: 132.98 – 132.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptotagmin-like protein 1 is a protein that in humans is encoded by the SYTL1 gene.[5][6]

Interactions

SYTL1 has been shown to interact with RAB27A.[7][8][9]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000142765 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028860 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Catz SD, Babior BM, Johnson JL (November 2002). "JFC1 is transcriptionally activated by nuclear factor-kappaB and up-regulated by tumour necrosis factor alpha in prostate carcinoma cells". The Biochemical Journal. 367 (Pt 3): 791–9. doi:10.1042/BJ20020345. PMC 1222920. PMID 12137562.
  6. ^ "Entrez Gene: SYTL1 synaptotagmin-like 1".
  7. ^ Fukuda M (April 2003). "Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells". The Journal of Biological Chemistry. 278 (17): 15390–6. doi:10.1074/jbc.M213090200. PMID 12590134.
  8. ^ Strom M, Hume AN, Tarafder AK, Barkagianni E, Seabra MC (July 2002). "A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport". The Journal of Biological Chemistry. 277 (28): 25423–30. doi:10.1074/jbc.M202574200. PMID 11980908.
  9. ^ Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (March 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". The Journal of Biological Chemistry. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.

Further reading

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