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TUG1
Identifiers
Aliases	TUG1, LINC00080, NCRNA00080, TI-227H, taurine up-regulated 1 (non-protein coding)
External IDs	OMIM: 614971; GeneCards: TUG1
Orthologs
Databases	NCBI: entry; OMA: entry
	55000
	n/a
	ENSG00000253352
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

TUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in the retina and in the brain. It was first identified in a screen for genes upregulated by in developing retinal cells in response to taurine. It is required for the normal development of photoreceptors in the retina.^[2]

References

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Young TL, Matsuda T, Cepko CL (March 2005). "The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina". Curr. Biol. 15 (6): 501–512. Bibcode:2005CBio...15..501Y. doi:10.1016/j.cub.2005.02.027. PMID 15797018. S2CID 14573295.

Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Wang AG, Yoon SY, Oh JH, et al. (2006). "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags". Biochem. Biophys. Res. Commun. 345 (3): 1022–1032. Bibcode:2006BBRC..345.1022W. doi:10.1016/j.bbrc.2006.04.175. PMID 16712791.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Brandenberger R, Wei H, Zhang S, et al. (2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–716. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Ishiguro T, Nakajima M, Naito M, et al. (1996). "Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials". Cancer Res. 56 (4): 875–879. PMID 8631027.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.

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[1] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15797018-2] Young TL, Matsuda T, Cepko CL (March 2005). "The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina". Curr. Biol. 15 (6): 501–512. Bibcode:2005CBio...15..501Y. doi:10.1016/j.cub.2005.02.027. PMID 15797018. S2CID 14573295.

[1]

[2]

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TUG1

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