Taxoid

Not to be confused with Toxoid.

Taxoids are a class of derivatives from taxol,[1] that is, paclitaxel. They were developed for their anticancer chemotherapeutic properties. Taxoids are usually treated as synonymous with taxanes; for example, a major medical dictionary defines the two terms with the same definition phrasing,[2] and in another the phrasing varies slightly but conveys nearly identical meaning.[3]

Taxoids are chemically taxane-derived diterpenoids, which do occur in nature, in the genera Taxus and Austrotaxus of yew trees.[4] The taxoids class and the taxanes class both include paclitaxel (trade names Taxol, Abraxane, Onxol, Nov-Onxol) and docetaxel (trade names Taxotere, Docecad).

References

  1. ^ "Taxoids: New Weapons against Cancer" (PDF). 1996.
  2. ^ Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.
  3. ^ Wolters Kluwer, Stedman's Medical Dictionary, Wolters Kluwer.
  4. ^ Timmerman, H. (16 June 1995). The Chemistry and Pharmacology of Taxol® and its Derivatives. Elsevier. p. 7. ISBN 978-0-08-054499-1.


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