UBL3

UBL3

Identifiers

UBL3, HCG-1, PNSC1, ubiquitin like 3

External IDs

OMIM: 604711; MGI: 1344373; GeneCards: UBL3

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2GOW

Gene location (Human)

Chr.	Chromosome 13 (human)^[1]

Band	13q12.3	Start	29,764,371 bp^[1]
Band	13q12.3	End	29,850,617 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)^[2]

Band	5\|5 G3	Start	148,504,635 bp^[2]
Band	5\|5 G3	End	148,552,789 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

inferior olivary nucleus

amniotic fluid

dorsal motor nucleus of vagus nerve

pars reticulata

subthalamic nucleus

pars compacta

external globus pallidus

superior vestibular nucleus

postcentral gyrus

Region I of hippocampus proper

Top expressed in

extensor digitorum longus muscle

Rostral migratory stream

plantaris muscle

corneal stroma

extraocular muscle

olfactory epithelium

cardiac muscle tissue of left ventricle

CA3 field

dorsal striatum

spermatid

More reference expression data


More reference expression data

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


5412


24109


ENSG00000122042


ENSMUSG00000001687


O95164


Q9Z2M6

RefSeq (mRNA)


NM_007106


NM_011908

RefSeq (protein)


NP_009037


NP_036038 NP_001346128 NP_001346129 NP_001346130 NP_001346131

Location (UCSC)

Chr 13: 29.76 – 29.85 Mb

Chr 5: 148.5 – 148.55 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Ubiquitin-like protein 3 is a protein that in humans is encoded by the UBL3 gene.^[5]^[6]

In melanocytic cells UBL3 gene expression may be regulated by MITF.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122042 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001687 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chadwick BP, Kidd T, Sgouros J, Ish-Horowicz D, Frischauf AM (Aug 1999). "Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene". Gene. 233 (1–2): 189–95. doi:10.1016/S0378-1119(99)00138-9. PMID 10375635.
^ "Entrez Gene: UBL3 ubiquitin-like 3".
^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Downes BP, Saracco SA, Lee SS, et al. (2006). "MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation". J. Biol. Chem. 281 (37): 27145–57. doi:10.1074/jbc.M602283200. PMID 16831869.

v t e PDB gallery
1wgh: Solution Structure of Mouse Ubiquitin-like 3 Protein 2gow: Solution structure of BC059385 from Homo sapiens

This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.