The UL Bend Wilderness comprises almost half the refuge (20,819 acres (84 km2)) and provides a high level of protection to the most remote regions. There are no maintained trails in the wilderness area and the only access is either on foot or horseback. The Upper Missouri Breaks National Monument is located immediately west of the wilderness. Broken into three sections, the largest portion of the wilderness is characterized by steep sided cliffs of the Missouri River "Breaks" country.
The Lewis and Clark Expedition passed through this region and wrote extensively on the abundance of wildlife and the ruggedness of the countryside.
The black-footed ferret has been reintroduced into the refuge in the 1990s after nearing extinction; the sustainability of this relocated species is not yet known, and there are only 1,000 remaining in breeding compounds and perhaps 100 in the wild. Researchers in 2002 were only able to locate a total of 5 ferrets in the entire refuge.
A proposal for the reintroduction of bison was submitted in 2020.[1]
Access
This refuge is remote, requiring travel by gravel and dirt roads that can be difficult to navigate during inclement weather.