In the aftermath of a massacre of white settlers by local indigenous people in 18th century colonial America, frontiersman and guide Daniel Boone is sent by British General Braddock to search for survivors. Among them is Charlie Bryan, who reports that his two daughters were carried away by the Indians. Boone rescues the young women, Rebecca and Helen. A French captain, Fraser, representing French colonial interests, captures Boone and his party. An attack by Indians in alliance with British forces leads to a fight, in which Boone kills Captain Fraser. Boone and Rebecca intend to marry and settle in Kentucky.