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RNF115
Identifiers
Aliases	RNF115, BCA2, ZNF364, ring finger protein 115, ZFP364, RABRING7
External IDs	MGI: 1915095; GeneCards: RNF115
Enzyme activity
Gene location (Human)
Chr.	Chromosome 1 (human)
End	145,824,095 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	96,698,954 bp
RNA expression pattern
	Top expressed in
	glutes; ; right ventricle; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; Skeletal muscle tissue of biceps brachii; ; paraflocculus of cerebellum; ; tail of epididymis; ; myocardium; ; vastus lateralis muscle; ; myocardium of left ventricle;
	Top expressed in
	soleus muscle; ; substantia nigra; ; vastus lateralis muscle; ; barrel cortex; ; intercostal muscle; ; motor neuron; ; facial motor nucleus; ; trigeminal ganglion; ; tibialis anterior muscle; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; transferase activity;
Cellular component	cytoplasm; cytosol;
Biological process	protein K63-linked ubiquitination; protein K48-linked ubiquitination; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; negative regulation of epidermal growth factor receptor signaling pathway; protein ubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; protein autoubiquitination; protein polyubiquitination;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	27246
	67845
	ENSG00000265491
	ENSMUSG00000028098
	Q9Y4L5
	Q9D0C1
	NM_014455
	NM_026406
	NP_055270
	NP_080682
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein 115 is a protein, that in humans, is encoded by the RNF115 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000265491 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028098 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ZNF364 zinc finger protein 364".

Burger A, Amemiya Y, Kitching R, Seth AK (2006). "Novel RING E3 ubiquitin ligases in breast cancer". Neoplasia. 8 (8): 689–95. doi:10.1593/neo.06469. PMC 1601945. PMID 16925951.
Sakane A, Hatakeyama S, Sasaki T (2007). "Involvement of Rabring7 in EGF receptor degradation as an E3 ligase". Biochem. Biophys. Res. Commun. 357 (4): 1058–64. doi:10.1016/j.bbrc.2007.04.052. PMID 17462600.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Burger AM, Gao Y, Amemiya Y, et al. (2006). "A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer". Cancer Res. 65 (22): 10401–12. doi:10.1158/0008-5472.CAN-05-2103. PMID 16288031.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Mizuno K, Kitamura A, Sasaki T (2004). "Rabring7, a novel Rab7 target protein with a RING finger motif". Mol. Biol. Cell. 14 (9): 3741–52. doi:10.1091/mbc.E02-08-0495. PMC 196564. PMID 12972561.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMC 311163. PMID 11591653.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000265491 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028098 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ZNF364 zinc finger protein 364".

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ZNF364

References

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