TLE2

TLE2
식별자
다른 이름TLE2, ESG, ESG2, GRG2, transducin like enhancer of split 2, TLE family member 2, transcriptional corepressor
외부 IDOMIM: 601041 MGI: 104635 HomoloGene: 20693 GeneCards: TLE2
RNA 발현 패턴
Bgee
인간쥐(동원체)
최상위 발현
  • cerebellar hemisphere

  • right hemisphere of cerebellum

  • cerebellar vermis

  • 정강신경

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • 왼자궁관

  • 귀밑샘

  • apex of heart

  • 장딴지신경
최상위 발현
  • cerebellar cortex

  • neural layer of retina

  • medullary collecting duct

  • lobe of cerebellum

  • cerebellar vermis

  • primary visual cortex

  • 속목동맥

  • 부신

  • superior frontal gyrus

  • 대구치
추가 참조 발현 데이터
BioGPS


추가 참조 발현 데이터
위키데이터
인간 보기/편집쥐 보기/편집

트랜스듀신 유사 증폭자 단백질 2(Transducin-like enhancer protein 2 )는 인간에서 TLE2 유전자에 의해 암호화되는 단백질이다.[5][6]

상호 작용

TLE2는 TLE1[7] 및 HES1과 상호 작용하는 것으로 나타났다.

각주

  1. ↑ 가 나 다 GRCh38: Ensembl release 89: ENSG00000065717 - 앙상블, May 2017
  2. ↑ 가 나 다 GRCm38: Ensembl release 89: ENSMUSG00000034771 - 앙상블, May 2017
  3. ↑ “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》. 
  4. ↑ “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》. 
  5. ↑ “Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia”. 《Genomics》 31 (1): 58–64. Oct 1996. doi:10.1006/geno.1996.0009. PMID 8808280. 
  6. ↑ “Entrez Gene: TLE2 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)”. 
  7. ↑ Grbavec, D; Lo R; Liu Y; Stifani S (Dec 1998). “Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development”. 《Eur. J. Biochem.》 (GERMANY) 258 (2): 339–49. doi:10.1046/j.1432-1327.1998.2580339.x. ISSN 0014-2956. PMID 9874198. 

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