食用胭脂樹紅對大多數人來說都是沒有危險的,但是極少數人會對其產生過敏反應。[19][20]曾有幾起對胭脂樹紅的過敏記錄,但是它並不是所謂的“八大過敏原”(牛奶、蛋、花生、堅果、魚、貝類、大豆、麥)之一。[21]美國食品藥品監督管理局和內布拉斯加大學食物過敏研究及資源項目(Food Allergy Research and Resource Program)的專家不認為它應當算是一種主要過敏原。[22]
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