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DCW234

DCW234
臨床資料
其他名稱Butyl 4-(butyryloxy)benzoate
识别信息
  • butyl 4-butanoyloxybenzoate
CAS号723759-26-0
PubChem CID
ChemSpider
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)
化学信息
化学式C15H20O4
摩尔质量264.32 g·mol−1
3D模型（JSmol（英语：JSmol））
  • CCCCOC(=O)C1=CC=C(C=C1)OC(=O)CCC
  • InChI=1S/C15H20O4/c1-3-5-11-18-15(17)12-7-9-13(10-8-12)19-14(16)6-4-2/h7-10H,3-6,11H2,1-2H3
  • Key:LMJDPYAJKHNPHR-UHFFFAOYSA-N

DCW234（化学名：对丁酸基苯甲酸丁酯，Butyl 4-(butyryloxy)benzoate）是一种人工合成的非甾体雌激素和ERβ的选择性激动剂。[1][2][3]

参考文献

  1. ^ Lin Z, Shen H, Huang J, Chen S, Chen L, Chen J, Liu G, Jiang H, Shen X. Butyl 4-(butyryloxy)benzoate functions as a new selective estrogen receptor beta agonist and induces GLUT4 expression in CHO-K1 cells. J. Steroid Biochem. Mol. Biol. 2008, 110 (1–2): 150–6. PMID 18455388. S2CID 206496235. doi:10.1016/j.jsbmb.2008.03.028. 
  2. ^ Minutolo F, Macchia M, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor β ligands: recent advances and biomedical applications. Med Res Rev. 2011, 31 (3): 364–442. PMID 19967775. S2CID 3841877. doi:10.1002/med.20186. 
  3. ^ Serock MR, Wells AK, Khalil RA. Modulators of vascular sex hormone receptors and their effects in estrogen-deficiency states associated with menopause. Recent Pat Cardiovasc Drug Discov. 2008, 3 (3): 165–86. PMID 18991792. doi:10.2174/157489008786263970. 

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