COG1

COG1
Pengidentifikasi
AliasCOG1, CDG2G, LDLB, component of oligomeric golgi complex 1
ID EksternalOMIM: 606973; MGI: 1333873; HomoloGene: 8411; GeneCards: COG1; OMA:COG1 - orthologs
Ortologi
SpesiesManusiaTikus
Entrez

9382

16834

Ensembl

ENSG00000166685

ENSMUSG00000018661

UniProt

Q8WTW3

Q9Z160

RefSeq (mRNA)

NM_018714

NM_013581

RefSeq (protein)

NP_061184

NP_038609

Location (UCSC)Chr 17: 73.19 – 73.21 Mbn/a
PubMed search[2][3]
Wikidata
Lihat/Sunting ManusiaLihat/Sunting Tikus

Subunit oligomer golgi kompleks 1 adalah protein yang pada manusia dikodekan oleh gen COG1.[4][5]

Protein yang dikodekan oleh gen ini merupakan satu dari delapan protein (Cog1-8) yang membentuk kompleks Golgi-lokal (COG) yang dibutuhkan untuk morfologi Golgi normal dan fungsinya. Diperkirakan bahwa protein ini diperlukan untuk langkah-langkah dalam pemrosesan glikokonjonjara transial dan trans Golgi yang normal dan memainkan peran dalam pengorganisasian kompleks Golgi-lokal

Interaksi

COG1 telah diketahui berinteraksi dengan COG4[6] dan COG3.[7]

Referensi

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166685 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M (Mar 1999). "Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex". Proc Natl Acad Sci U S A. 96 (3): 915–20. doi:10.1073/pnas.96.3.915. PMC 15325. PMID 9927668.
  5. ^ "Entrez Gene: COG1 component of oligomeric golgi complex 1".
  6. ^ Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. 279 (23). United States: 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703. {{cite journal}}: Kutipan memiliki paramater tidak diketahui s: |laysummary=, |laydate=, and |laysource=Pemeliharaan CS1: DOI bebas tanpa ditandai (link)
  7. ^ Loh, Eva; Hong Wanjin (Jun 2002). "Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp". J. Biol. Chem. 277 (24). United States: 21955–61. doi:10.1074/jbc.M202326200. ISSN 0021-9258. PMID 11929878. {{cite journal}}: Kutipan memiliki paramater tidak diketahui s: |laysummary=, |laydate=, and |laysource=Pemeliharaan CS1: DOI bebas tanpa ditandai (link)

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