Andre Agassi defeated the defending champion Pete Sampras in the final, 4–6, 6–1, 7–6(8–6), 6–4 to win the men's singles tennis title at the 1995 Australian Open. It was his first Australian Open title and third major title overall. Agassi was making his tournament debut, and would go on to win three more editions of the tournament in 2000, 2001, and 2003.
A memorable moment occurred in the quarterfinal match between Sampras and Jim Courier. Sampras had fought from a two-set deficit to level the match at 2–2. Shortly after winning the first game of the fifth set, Sampras was overcome with grief over his then-coach, Tim Gullikson. (Gullikson had suffered several seizures while touring with Sampras in Europe in late 1994. Shortly before Sampras' match against Courier, Gullikson had collapsed during a practice session after suffering another seizure, with tests proving inconclusive at Epworth Hospital and being flown home to Chicago for further tests.) During the fifth set of the match, Sampras retired to his chair and broke down in tears. When he returned, Courier offered to finish the match the next day. Sampras declined and then won the match. Gullikson was later diagnosed with inoperable brain cancer and died in May 1996.
Seeds
The seeded players are listed below. Andre Agassi is the champion; others show the round in which they were eliminated.