The town is not served by any paved roads, with the Pan-American Highway to the north ending at Yaviza. It is reachable by boat up the Tuira River. Civilians are not permitted to travel farther east towards Colombia.[2][3]
In the early 1900s, a single-gage railway ran to the town from the Cana gold mines.[4] It ceased operating in 1911.[5]
Villages within the corregimiento farther up the river include Sobiaquirú.[6]
^Moon Central America (2016) ("Travel up the Rio Tuira beyond Boca de Cupe is considered dangerous and has been off-limits for several years. Boca de Cupe itself has a border-police post, but that doesn't necessarily make it safe.")
^(1 March 2018). ARAP participa de Gira Interinstitucional en Sobiaquirú, provincia de Darién, La Autoridad de Recursos Acuáticos de Panamá (Translated sentence from Spanish: "The place of destination was the indigenous population of Sobiaquirú located in Alto Tuira of the Corregimiento of Boca de Cupe, province of Darién.")