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GD-42

GD-42
Names
Preferred IUPAC name
4,8-Dimethyl-4-oxo-3-oxa-5,8-dithia-4λ5-phosphadecan-8-ium methyl sulfate
Other names
Methylsulfomethylate
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C8H20O2PS2.CH4O4S/c1-5-10-11(3,9)12-7-8-13(4)6-2;1-5-6(2,3)4/h5-8H2,1-4H3;1H3,(H,2,3,4)/q+1;/p-1
    Key: AUACWHVUVIIDOR-UHFFFAOYSA-M
  • CCOP(=O)(C)SCC[S+](C)CC.COS(=O)(=O)[O-]
Properties
C9H23O6PS3
Molar mass 354.43 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

GD-42 (methylsulfomethylate) is an irreversible acetylcholinesterase inhibitor.[1][2] It has a positively charged sulfonium group.

See also

References

  1. ^ Danilov, AF; Kvitko, IJ; Lavrentieva, VV; Michelson, MJ; Porai-Koshits, BA; Rozhkova, EK; Shelkovnikov, SA (April 1972). "Action of some bisquaternary derivatives of phthalic acids and related substances on neuromuscular transmission". British Journal of Pharmacology. 44 (4): 765–78. doi:10.1111/j.1476-5381.1972.tb07314.x. PMC 1665980. PMID 4339387.
  2. ^ Danilov, AF; Ivanov, YJ; Michelson, MJ (January 1976). "The influence of motor nerve tetanization on the effect of organophosphorus cholinesterase inhibitors on neuromuscular transmission". British Journal of Pharmacology. 56 (1): 115–23. doi:10.1111/j.1476-5381.1976.tb06966.x. PMC 1666757. PMID 175873.
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