Moffitt Cancer Center & Research Institute is a nonprofit cancer treatment and research center located in Tampa, Florida. Established in 1981 by the Florida Legislature, the hospital opened in October 1986 on the University of South Florida's campus.[2] Moffitt is one of two National Cancer Institute-designated Comprehensive Cancer Centers based in Florida.[3][4][5] In 2021, U.S. News & World Report ranked Moffitt Cancer Center as a top 30 cancer hospital in the United States.[6][7]
History
Funding for construction of the initial $70 million facility came primarily from the state of Florida's cigarette tax, while the momentum to create the center came from a cadre of legislators, physicians, educators, and business leaders who envisioned a new dimension of cancer care and research in Florida.
In late 1978, H. Lee Moffitt, a Florida state representative, recognized the need for a comprehensive cancer center within the state after several friends died from cancer. An excellent negotiator, Moffitt put his plan into motion by first proposing the idea to Hollis Boren, then dean of the University of South Florida College of Medicine. Over lunch at the Tampa Club, Moffitt proposed his idea. By dessert, Boren has signed on. "Out of that discussion came plans for a plug-shaped, multilevel cancer research teaching hospital to be built a short walk away from the USF clinics," The Tampa Times reported on February 5, 1979. Moffitt and Boren had gathered information about the need for a comprehensive cancer center, the article said, and the need was great.[8][9]
Moffitt sought community support and convinced the State Legislature to fund the facility. During the center's planning phase, consultants associated with NCI-designated Cancer Centers were retained to ensure that the finished facility would be as technologically advanced and as efficiently designed as possible.
Groundbreaking ceremonies took place in January 1983. The center was incorporated in the spring of 1984 and was named for Houston Lee Moffitt, then Speaker of the State House of Representatives. The building was dedicated in October 1986 and admitted its first patients that same month.
In 1990, the acquisition of the Research Center building across from the Cancer Center enhanced the recruitment of scientists, clinicians, and support staff, and expanded Moffitt's vision beyond the original structure. The Moffitt Research Center became the focal point for basic and translational cancer research, with the overriding goal to produce discoveries that could be translated quickly from the bench to the patient's bedside. The Florida Legislature allocated $12 million for renovation and equipment for this 100,000-square-foot (9,300 m2) structure, and the Moffitt Research Center became fully operational in 1995. In 1999, 48,000 square feet (4,500 m2) of basic research lab space was added to the Moffitt Research Center at a cost of $11 million to house the growing need for additional scientists.
In 2022 the Florida Legislature approved more than $706 million for a new H. Lee Moffitt Cancer Center and Research Institute campus in Pasco County. $600 million in state funding will be distributed in yearly in $20 million yearly increments for each of the next 30 years.[10]
Organization
On June 10, 1998, in a ceremonial signing at Moffitt, Florida governorLawton Chiles approved a legislative initiative to fund construction of the Moffitt Tower Project, which opened in April 2003, adding more than 350,000 square feet (33,000 m2) of new space. This expansion includes the Vincent A. Stabile Research Building, eponymously named in recognition of the largest private donation ever made to the Cancer Center. The new construction also includes an expansion of the Moffitt Clinic. In addition to new research laboratories, which nearly double the cancer center's research capabilities, the new facilities include a digital imaging center, and a new infusion center.
In 1991, John Ruckdeschel, assumed the position of center director, president and CEO. Under Ruckdeschel's leadership, Moffitt became a National Cancer Institute (NCI) Comprehensive Cancer Center. In 2017,[11] the NCI renewed Moffitt's Cancer Center Support Grant for another five years. Currently, Moffitt receives more than $50 million annually in peer-reviewed grant monies.
In 2002, Ruckdeschel stepped down, and William Dalton, became Moffitt's third president, CEO and center director.
On June 24, 2011, Moffitt Cancer Center opened the first blood and marrow transplant (BMT) clinic in Puerto Rico.[19]
On July 1, 2011, Moffitt Cancer Center opened a new 50,000-square-foot satellite facility at International Plaza. The building replaced Moffitt's former outpatient center at Tampa General Hospital.[20][21]
In July 2012, William Dalton, became the CEO of M2Gen and Moffitt's new Personalized Medicine Institute. Alan List, who previously served as Moffitt's executive vice president/physician-in-chief and president of the Moffitt Medical Group, succeeded Dalton as CEO and president. Thomas Sellers assumed the role of center director.[22]
In February 2013, Moffitt began construction of a $74.2 million outpatient facility on the cancer center's 30-acre property on N McKinley Drive, about a mile from Moffitt's main campus.[23]
In November 2015, Moffitt opens the McKinley Outpatient Center. The six-story, 207,000-square-foot facility at 10920 N McKinley Drive is located about a mile from the main campus. Services on the site include the skin and breast cancer clinics, four operating rooms, an imaging suite, research labs, space for blood draws and a Publix pharmacy.[24]
In July 2017, Moffitt and Memorial Healthcare announce a partnership to establish a comprehensive blood and marrow transplant cellular therapy program for South Florida residents. The alliance brings the renowned cancer center's access to research, clinical trials, and comprehensive treatment to leukemia, lymphoma and multiple myeloma patients.[25]
In August 2020, Moffitt named Patrick Hwu, a tumor immunologist with 33 years of oncology experience, its new president and CEO.[26]
Research and Treatment
Through clinical trials, Jeffrey Weber, director of the Donald A. Adam Comprehensive Melanoma Research Center at Moffitt, and researchers at Moffitt Cancer Center discovered two monotherapy drugs – Mekinist (trametinib) and Tafinlar (dabrafenib) – can be safely combined to overcome or delay treatment resistance for a large percentage of melanoma patients with a specific gene mutation. Approved by the FDA in January 2014, Mekinist in combination with Tafinlar is one of the biggest advancements in melanoma treatment in the past 30 years.[27]
In August 2011, the U.S. Food and Drug Administration (FDA) approved the drug vemurafenib (Zelboraf) for metastatic melanoma patients who test positive for a specific gene mutation. Moffitt Cancer Center conducted a registration trial using the drug manufactured by Genentech, a member of the Roche Group.[28]
Anna Giuliano, director of Moffitt's Center for Infection Research in Cancer, led two studies on human papillomavirus (HPV) infection in men. Her work strengthened the Food & Drug Administration (FDA) recommendation for boys and men to receive HPV vaccinations and provided useful data for the development of realistic cost-effectiveness models for male HPV vaccination internationally.[29]
In September 2014, a new cancer immunotherapy for melanoma patients called Keytruda became the first anti-PD-1 (programmed death receptor-1) therapy approved in the United States. Jeffrey Weber, director of the Donald A. Adam Comprehensive Melanoma Research Center of Excellence at Moffitt, was one of the lead investigators of the clinical trial which led to the drug receiving breakthrough status from the FDA.[30]
In January 2016, researchers at Moffitt teamed up with the state of Florida in a study to see if making fruits and vegetables available to children who otherwise may not have them readily available can decrease their risk of cancer.[31]
In October 2017, the Food and Drug Administration announced the approval of Yescarta™, a revolutionary new immunotherapy for adult patients with diffuse large B cell lymphoma, a form of non-Hodgkin's lymphoma. Yescarta is a Chimeric Antigen Receptor (CAR) T cell therapy, also known as CAR-T. Moffitt Cancer Center's Frederick Locke, is the co-lead investigator of the pivotal ZUMA-1 clinical trial that tested the new therapy, which is manufactured by Kite, a Gilead company.[32]
In February 2024, the U.S. Food and Drug Administration approved a first-of-its-kind immunotherapy pioneered at Moffitt for patients with advanced melanoma.[33] Moffitt was a driving force in getting lifileucel (Amtagvi) FDA-approved for the treatment of adult patients with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody, and if BRAF V600 mutation positive, a BRAF inhibitor with or without a MEK inhibitor.[34]
Moffit Cancer Center is located on the campus of the University of South Florida in north Tampa. The center includes the hospital, Muriel Rothman Building (clinic), Vincent A. Stabile Research Building and the Moffitt Research Center.[38]
Moffitt at International Plaza is a 50,000-square-foot full service outpatient facility near Tampa International Airport. The facility includes physician office visits, infusion services, radiation and radiology.[39]
Moffitt Cancer Center Prevention Research, Fowler Campus, located in north Tampa, is a facility that practices research for prevention and early detection of cancer.[40]
The Richard M. Schulze Family Foundation Outpatient Center at McKinley Campus,[41] 10920 N. McKinley Drive, includes the breast and skin cancer clinics, infusion center, research labs and four surgery suites.[42]
Moffitt Malignant Hematology & Cellular Therapy at Memorial Healthcare System, 801 N. Flamingo Road, Pembroke Pines, FL, provides a comprehensive Blood and Marrow Transplant Cellular Therapy Program for South Florida residents.[43]
Moffitt Cancer Center at Wesley Chapel, 2590 Healing Way, Wesley Chapel, FL, is a 28,000-square-foot outpatient facility bringing access to Moffitt expertise and nationally-ranked cancer care to Pasco County.[44]
Moffitt McKinley Hospital, 10901 N. McKinley Drive, Tampa, FL, is an inpatient surgical hospital located on Moffitt's McKinley Campus. The 10-story, 500,000-square-foot facility provides patients with the latest innovations in surgical techniques and inpatient care.[45]
Moffitt Cancer Center at Port Tampa Bay, 651 Channelside Drive, Tampa, FL, is a community outreach and education center near downtown Tampa.[46]
Recognition
From 1999 to 2019, Moffitt has been ranked one of "America's Best Hospitals" for cancer by U.S. News & World Report.[47]
In 2014, Becker's Hospital Review includes Moffitt in the 100 Accountable Care Organizations to Know.[48]
In 2015, Moffitt earned a Magnet designation for nursing excellence, granted by the American Nurses Credentialing Center (ANCC), the credentialing body of the American Nurses Association.[49][verification needed]
In 2015, Becker's Hospital Review recognizes Moffitt's president and CEO Dr. Alan List in its "100 Physician Leaders of Hospitals and Health Systems."[50]
Moffitt Cancer Center was named 2017 Nonprofit of the Year by the Tampa Bay Business Journal. Moffitt was also recognized as the category winner in the Health & Human Services category.[51]
In 2018, Moffitt was named LGBTQ Healthcare Equality Leader by the Human Rights Campaign Foundation.[52] The cancer center was also named one of Working Mother Magazine's 100 Best Companies for 10th time.[53]
In 2023, Moffitt was ranked No. 10 in the nation and the top-ranked cancer hospital in Florida and the Southeast in Newsweek’s 2023 list of “America’s Best Cancer Hospitals.”[54]
Mappa dei sistemi giuridici del mondo[1] Il civil law (in italiano detto anche diritto continentale o diritto romano-germanico)[2] è un modello di ordinamento giuridico derivante dal diritto romano, oggi dominante a livello mondiale.[3] Spesso è contrapposto ai modelli di common law dei paesi anglofoni. I sistemi di civil law si sono sviluppati dapprima nell'Europa continentale e poi, in moltissimi stati del pianeta, all'interno della cornice dottrinaria del diritto rom…
Ludwig Andreas von FeuerbachLudwig Andreas von FeuerbachLahir(1804-07-28)28 Juli 1804Landshut, BavariaMeninggal13 September 1872(1872-09-13) (umur 68)Rechenberg dekat Nürnberg, Kekaisaran JermanEraFilsafat abad ke-19KawasanFilsafat BaratAliranMaterialisme, HumanismeMinat utamaAgama, KekristenanGagasan pentingAgama sebagai proyeksi luar dari sifat batin manusia Dipengaruhi Hegel Memengaruhi Leconte de Lisle, Karl Marx, Friedrich Engels, Mikhail Bakunin, Max Stirner, Joseph Dietzge…
Untuk Bekas negara di Asia, lihat Pala (Anatolia). Pala Pala Klasifikasi ilmiah Kerajaan: Plantae (tanpa takson): Angiospermae (tanpa takson): Magnoliids Ordo: Magnoliales Famili: Myristicaceae Genus: Myristica Spesies: M. fragrans Nama binomial Myristica fragrans Pala (Myristica fragrans) merupakan tumbuhan berupa pohon yang berasal dari kepulauan Banda, Maluku. Akibat nilainya yang tinggi sebagai rempah-rempah, buah dan biji pala telah menjadi komoditas perdagangan yang penting sejak masa…
We Can Make It!Lagu oleh Arashidari album TimeSisi-BDi-Li-LiDirilis02 Mei 2007 (2007-05-02)FormatCDGenrePopLabelJ StormJACA-5059 (Edisi Terbatas)JACA-5060 (Edisi Normal)Kronologi singel Love So Sweet (2007) We Can Make It! (2007) Happiness (2007) We Can Make It! adalah single ke-19 boyband Jepang Arashi. Single ini dirilis dalam 2 edisi: satu edisi regular yang berisi versi karaoke dari seluruh lagu yang termasuk dalam single, dan yang satunya edisi terbatas yang berisi sebuah bonus trek da…
Pertemuan Volksdeutsche di wilayah pendudukan Warsawa pada tahun 1940 Deutsche Volksliste (Dewan Rakyat Jerman) adalah sebuah lembaga Partai Nazi yang ditujukan untuk mengklasifikasikan wilayah pendudukan Nazi (1939-1945) ke dalam kategori-kategori yang selaras dengan kriteria yang ditentukan oleh Reichsführer-SS Heinrich Himmler. Lembaga tersebut berawal di wilayah pendudukan Polandia barat (diduduki pada 1939-1945). Skema-skema serupa kemudian dikembangkan di wilayah pendudukan Prancis (1940-…
Liburan Seruuu...!!SutradaraSofyan D SurzaProduserAri SihasaleNia ZulkarnaenDitulis olehTian Pranyoto GafarPemeranKen Nala AmrythaRaja Intan PermataArsenna Moch. RahadiQuinsha Jasmine HaqMinus C. KarobaDonny DamaraIra WibowoCynthia LamusuBerliana FebriantiAlvin AdamPenata musikDian HPSinematograferYudi DatauPenyuntingAndhy PulungDistributorAlenia PicturesTanggal rilis3 Juli 2008Durasi97 menitNegara IndonesiaBahasaBahasa Indonesia Liburan Seruuu...!! merupakan film drama anak-anak tahun 200…
Marco Pierre WhiteWhite pada tahun 2012 di Melbourne, AustraliaLahir11 Desember 1961 (umur 62)Leeds, West Riding of Yorkshire, InggrisSuami/istriAlex McArthur (m. 1988–Kesalahan ekspresi: Operator < tak terduga) (cerai)Lisa Butcher (m. 1992, cerai)Mati Conejero (m. 2000–sekarang)(pisah)[1]Karier kulinerGaya masakMasakan Prancis, Britania dan Italia Acara televisi Ramsay’s Boiling Point (1999) Situs webmarcopierrewhite.co Ma…
The Golden Voyage of SinbadPoster filmSutradaraGordon HesslerProduserCharles H. SchneerRay HarryhausenDitulis olehBrian ClemensRay HarryhausenPemeranJohn Phillip LawTom BakerTakis EmmanuelCaroline MunroDouglas WilmerMartin ShawPenata musikMiklós RózsaSinematograferTed Moore, BSCPenyuntingRoy WattsDistributorColumbia PicturesTanggal rilis5 April 1974Durasi105 menitNegaraBritania RayaBahasaInggrisAnggaran$982,351PrekuelThe 7th Voyage of SinbadSekuelSinbad and the Eye of the Tiger The Golde…
Walpole, difoto oleh Carl Van Vechten, 1934 Sir Hugh Seymour Walpole, CBE (13 Maret 1884 – 1 Juni 1941) adalah seorang novelis Inggris kelahiran Selandia Baru. Ia adalah putra dari biarawan Anglikan Ia adalah penulis dengan penjualan terbaik pada 1920an dan 1930an Biografi Tahun-tahun awal Walpole lahir di Auckland, Selandia Baru, sebagai anak sulung dari tiga bersaudara dari pasangan Rev Somerset Walpole dan istrinya, Mildred Helen, née Barham (1854–1925).[1] Catatan …
Dinas Kepurbakalaan Hindia Belanda (Belanda: Oudheidkundige Dienstcode: nl is deprecated ) adalah salah satu unit birokrasi di dalam pemerintahan Hindia Belanda. Dinas ini dibentuk pada tanggal 14 Juni 1913 melalui Keputusan Pemerintah (Gouvernementsbesluit) dan Lembaran Negara Hindia Belanda (Staatsblad van Nederlandsch-Indië) nomor 62 tahun 1913 dan berada di bawah Departemen Pendidikan, Ibadah, dan Industri Kerajinan Hindia Belanda (O&E). Wilayah kerja dari lembaga ini mencakup seluruh w…
34°38′36″N 50°52′49″E / 34.643472222222°N 50.880305555556°E / 34.643472222222; 50.880305555556 حوزة قم العلمية معلومات المؤسس عبد الكريم الحائري اليزدي التأسيس 1922 النوع جامعة دينية الموقع الجغرافي إحداثيات 34°38′36″N 50°52′49″E / 34.643472222222°N 50.880305555556°E / 34.643472222222; 50.880305555556 المدينة…
Pour les articles homonymes, voir Ezzelino. Ezzelino III da RomanoEzzelino III da RomanoFonctionSeigneurMarche trévisaneBiographieNaissance 25 avril 1194PadoueDécès 7 octobre 1259 (à 65 ans)SoncinoSépulture Forteresse de Soncino (en)Activités Condottiere, homme politiqueFamille Da RomanoPère Ezzelino IIFratrie Alberico da RomanoConjoint Selvaggia de Staufen (d)Parentèle Frédéric II du Saint-Empire (beau-père)Autres informationsParti politique GibelinsBlasonmod…
Disc-shaped frying pan originating from the Indian subcontinent For other uses, see Tava (disambiguation). This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Tava – news · newspapers · books · scholar · JSTOR (May 2020) (Learn how and when to remove this template message) A concave tawa designed for use in a home …
Butler LampsonBiographieNaissance 23 décembre 1943 (80 ans)WashingtonNom dans la langue maternelle Butler W. LampsonNationalité américaineFormation Université HarvardUniversité de Californie à BerkeleyActivités Informaticien, ingénieur, professeur d'universitéAutres informationsA travaillé pour Palo Alto Research CenterDigital Equipment CorporationMassachusetts Institute of TechnologyMicrosoftMembre de Académie nationale d'ingénierie des États-Unis (1984)Académie américaine d…
U.S. Women's Hard Court Championships 1990 Sport Tennis Data 26 marzo – 1º aprile Edizione 25a Superficie Cemento Campioni Singolare Monica Seles Doppio Kathy Jordan / Elizabeth Sayers-Smylie 1989 1991 L'U.S. Women's Hard Court Championships 1990 è stato un torneo di tennis giocato sul cemento. È stata la 26ª edizione del torneo, che fa parte della categoria Tier III nell'ambito del WTA Tour 1990. Si è giocato a San Antonio negli Stati Uniti, dal 26 marzo al 1º aprile 1990. Indice 1 Camp…
Sepak mula (paling tenar dengan istilah kick-off yang berasal dari bahasa Inggris, sesekali bisa disebut sebagai tendangan pembuka, atau sepak awal ) adalah hal-hal mengenai dasar pelaksanaan secara nyata tentang permulaan dan kelanjutan suatu pertandingan sepak bola yang akan dilakoni, dengan salah seorang pemain menendang bola dari titik tengah lapangan.[1] Sepak mula juga akan kembali dilakukan setelah masuknya bola ke dalam gawang yang dicetak salah satu di antara kedua regu sepak bo…
British Independent politician, MP for Leicester East Not to be confused with Claudia Weber. Claudia WebbeMPOfficial portrait, 2019Member of Parliamentfor Leicester EastIncumbentAssumed office 12 December 2019Preceded byKeith VazMajority6,019 (12.2%)Islington London Borough Councillorfor BunhillIn office6 May 2010 – 6 May 2021Preceded byDonna Boffa Personal detailsBornClaudia Naomi Webbe (1965-03-08) 8 March 1965 (age 59)Leicester, EnglandPolitical partyIndependentOther polit…
Steve Buscemi nel 2018 Steve Buscemi, vero nome Steven Vincent Buscemi (New York, 13 dicembre 1957), è un attore, regista e doppiatore statunitense. Indice 1 Biografia 1.1 Origini 1.2 Carriera 1.3 Vita privata 2 Filmografia 2.1 Attore 2.1.1 Cinema 2.1.2 Televisione 2.2 Doppiatore 2.3 Regista 2.3.1 Cinema 2.3.2 Televisione 2.4 Produttore 2.5 Sceneggiatore 3 Riconoscimenti 4 Doppiatori italiani 5 Note 6 Altri progetti 7 Collegamenti esterni Biografia Origini Buscemi nasce a Brooklyn, borough di N…
Ця стаття потребує додаткових посилань на джерела для поліпшення її перевірності. Будь ласка, допоможіть удосконалити цю статтю, додавши посилання на надійні (авторитетні) джерела. Зверніться на сторінку обговорення за поясненнями та допоможіть виправити недоліки. Матер…