HEPBS

HEPBS
Chemical structure of HEPBS
Chemical structure of HEPBS
Names
Preferred IUPAC name
4-[4-(2-Hydroxyethyl)piperazin-1-yl]butane-1-sulfonic acid
Other names
HEPBS
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.157.294 Edit this at Wikidata
EC Number
  • 629-081-6
  • InChI=1S/C10H22N2O4S/c13-9-8-12-6-4-11(5-7-12)3-1-2-10-17(14,15)16/h13H,1-10H2,(H,14,15,16)
    Key: LOJNFONOHINEFI-UHFFFAOYSA-N
  • C1CN(CCN1CCCCS(=O)(=O)O)CCO
Properties
C10H22N2O4S
Molar mass 266.356 g/mol
Appearance White crystalline powder
Density 1.25 g/cm3 (predicted)
Melting point 211–216 °C (412–421 °F; 484–489 K)
Acidity (pKa) 8.3
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Irritant
GHS labelling:[1]
GHS07: Exclamation mark
Warning
H315, H319, H335
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Flash point Non-flammable
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

HEPBS (N-(2-Hydroxyethyl)piperazine-N'-(4-butanesulfonic acid)) is a zwitterionic organic chemical buffering agent; one of Good's buffers. HEPBS and HEPES have very similar structures and properties, HEPBS also having an acidity (pKa) in the physiological range (7.6-9.0 useful range). This makes it possible to use it for cell culture work.

HEPBS 1H NMR spectrum.

References

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.