Mayamycin

Mayamycin
Names
IUPAC name
1,6,8-Trihydroxy-5-[(2R,4R,5S,6R)-5-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]-3-methylbenzo[a]anthracene-7,12-dione
Other names
Mayamycin A
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C26H25NO7/c1-10-7-13-18(16(29)8-10)21-22(25(32)19-12(24(21)31)5-4-6-15(19)28)26(33)20(13)17-9-14(27-3)23(30)11(2)34-17/h4-8,11,14,17,23,27-30,33H,9H2,1-3H3/t11-,14-,17-,23-/m1/s1
    Key: ZVIQDPQQFMVLGU-XTCBYOQUSA-N
  • Cc1cc2c(c(c1)O)c3c(c(c2[C@H]4C[C@H]([C@@H]([C@H](O4)C)O)NC)O)C(=O)c5c(cccc5O)C3=O
Properties
C26H25NO7
Molar mass 463.486 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Mayamycin is a cytotoxic polyketide isolated from a marine Streptomyces.[1][2]

References

  1. ^ Schneemann, I; Kajahn, I; Ohlendorf, B; Zinecker, H; Erhard, A; Nagel, K; Wiese, J; Imhoff, J. F. (2010). "Mayamycin, a cytotoxic polyketide from a Streptomyces strain isolated from the marine sponge Halichondria panicea". Journal of Natural Products. 73 (7): 1309–12. doi:10.1021/np100135b. PMID 20545334.
  2. ^ Bo, Sheng Tao; Xu, Zi Fei; Yang, Li; Cheng, Ping; Tan, Ren Xiang; Jiao, Rui Hua; Ge, Hui Ming (June 2018). "Structure and biosynthesis of mayamycin B, a new polyketide with antibacterial activity from Streptomyces sp. 120454". The Journal of Antibiotics. 71 (6): 601–605. doi:10.1038/s41429-018-0039-x. ISSN 1881-1469. PMID 29515228. S2CID 256606240.


Stub icon

This article about an organic compound is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.