Menitazene

Menitazene
Identifiers
  • N,N-diethyl-2-[2-[(4-methylphenyl)methyl]-5-nitrobenzimidazol-1-yl]ethanamine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC21H26N4O2
Molar mass366.465 g·mol−1
3D model (JSmol)
  • CCN(CC)CCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)C
  • InChI=1S/C21H26N4O2/c1-4-23(5-2)12-13-24-20-11-10-18(25(26)27)15-19(20)22-21(24)14-17-8-6-16(3)7-9-17/h6-11,15H,4-5,12-14H2,1-3H3
  • Key:XGHTZJUKJYZDSW-UHFFFAOYSA-N

Menitazene (methylnitazene) is a benzimidazole derivative which has opioid effects and has been sold as a designer drug. It is considerably less potent than most of the "nitazene" group of opioids which have been sold on the illicit market, but still has around ten times the potency of morphine.[1][2][3][4]

See also

References

  1. ^ Hunger A, Kebrle J, Rossi A, Hoffmann K (1960). "Benzimidazole-Derivate und verwandte Heterocyclen III. Synthese von 1-Aminoalkyl-2-benzyl-nitro-benzimidazolen". Helvetica Chimica Acta. 43 (4): 1032–1046. doi:10.1002/hlca.19600430412.
  2. ^ Ujváry I, Christie R, Evans-Brown M, Gallegos A, Jorge R, de Morais J, et al. (April 2021). "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles". ACS Chemical Neuroscience. 12 (7): 1072–1092. doi:10.1021/acschemneuro.1c00037. PMID 33760580.
  3. ^ Hardwick EK, Davidson JT (July 2025). "Structural Characterization of Nitazene Analogs Using Electrospray Ionization-Tandem Mass Spectrometry (ESI-MS/MS)". Drug Testing and Analysis. doi:10.1002/dta.3921. PMID 40611807.
  4. ^ Deng Q, Xu J, Ni C, Cao F, Si Y, He S, et al. (2025). "Mass Fragmentation Characteristics of New Psychoactive Substances of Nitazenes". Journal of Chinese Mass Spectrometry Society. 46 (3): 334–342. doi:10.7538/zpxb.2024.0129 (inactive 17 August 2025).{{cite journal}}: CS1 maint: DOI inactive as of August 2025 (link)
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