Pretzsch lies in the middle of the Elbauen (natural polders along the Elbe), on the river's west bank which is on the northwest edge of the Düben Heath Nature Park. It is about 20 km southeast of Wittenberg and is the intersection of Federal Highway (Bundesstraße) B 182 between Torgau and Wittenberg, and state road (Landesstraße) L 128 between Bad Schmiedeberg and Jessen.
The SS Einsatzgruppen, the perpetrators of the initial phase of the Holocaust that preceded the invention of the more efficient Nazi death camp system, were first assembled at a police academy in Pretzsch in the spring of 1941.
Pretzsch Bahnhof, the heritage railway station which starred in the 2009 film The Last Station, standing in for the station in Astapovo, Russia where Leo Tolstoy died.[1]