Slovak football clubs have participated in European football competitions since 1956. Before 1993 Slovakia was a part of Czechoslovakia, therefore Slovak teams represented this country and did not always have a spot in European competitions.
All statistics and records are accurate as of 1 December 2020.
App. = Appearances; P = Matches played; W = Matches won; D = Matches drawn; L = Matches lost; Teams in italics currently do not play in the top division
The first qualifying round match between KÍ and Slovan Bratislava, originally scheduled to be played on 19 August 2020, was postponed to 21 August 2020 due to one player and one staff member from Slovan Bratislava testing positive for SARS-2 coronavirus and the whole team being put into quarantine by the Faroese authorities.[19] On 21 August, the match could not be played due to another player from Slovan Bratislava testing positive for SARS-2 coronavirus and the whole second team being put into quarantine by the Faroese authorities.[20][21] KÍ were subsequently awarded a technical 3–0 victory by UEFA according to the regulations related to COVID-19.[22]
For the 2022–23 UEFA competitions, the associations were allocated places according to their 2021 UEFA country coefficients, which take into account their performance in European competitions from 2016–17 to 2020–12. In the 2021 rankings used for the 2022–23 European competitions, Slovakia's coefficient points total is 13.625 and is ranked by UEFA as the 32nd best association in Europe out of 55.