Indometasin farnesil

Indometasin farnesil
Data klinis
AHFS/Drugs.comInternational Drug Names
Rute
pemberian		Oral
Kode ATC
  • None
Status hukum
Status hukum
  • ℞ (Hanya resep)
Data farmakokinetika
MetabolismeTo indometacin
Waktu paruh eliminasi1.5 hours
EkskresiRenal
Pengenal
  • (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate
Nomor CAS
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.242.585 Sunting di Wikidata
Data sifat kimia dan fisik
RumusC34H40ClNO4
Massa molar562,15 g·mol−1
Model 3D (JSmol)
  • CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC=C(C)CCC=C(C)CCC=C(C)C
  • InChI=1S/C34H40ClNO4/c1-23(2)9-7-10-24(3)11-8-12-25(4)19-20-40-33(37)22-30-26(5)36(32-18-17-29(39-6)21-31(30)32)34(38)27-13-15-28(35)16-14-27/h9,11,13-19,21H,7-8,10,12,20,22H2,1-6H3/b24-11+,25-19+ checkY
  • Key:CFIGYZZVJNJVDQ-LMJOQDENSA-N checkY
  (verify)

Indometacin farnesil adalah bakal obat dari Obat antiinflamasi nonsteroid, indometasin. Indometasin farnesil didesain untuk menurunkan efek samping melalui proses esterifikasi gugus karboksil indometasin menggunakan farnesol. Perizinan indometasin farnesil disetujui di Jepang pada tahun 1991, dan dipasarkan di Jepang, Filipina dan Indonesia dengan nama dagang Infree[1] dan Dialon.[2]

Referensi

  1. ^ "Infree". Drugs.com (dalam bahasa Inggris). Diarsipkan dari asli tanggal 2014-10-14. Diakses tanggal 2020-08-17.
  2. ^ "Dialon | PIO Nas". pionas.pom.go.id. Diakses tanggal 2020-08-17.

Pranala luar

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