The Sox entered the off-season expecting to part ways with 3B Joe Crede,[1] SS Orlando Cabrera,[2] and CF Ken Griffey Jr.[3] They were expected to move Rookie of the Year runner-up Alexei Ramírez to shortstop, leaving openings at second base, center field, and third base. There may also be opening in the starting rotation as José Contreras is not expected to be back until after the all-star break, as he recovers from a ruptured Achilles tendon.[needs update]
October 30, 2008 – Signed infielder Jayson Nix to a one-year deal. Declined 2009 options on catcher Toby Hall and Ken Griffey Jr.[4]
The White Sox started the season against the Royals on April 7 (originally scheduled for April 6 but postponed due to cold and snow), winning 4–2. On April 13 in Detroit, 3rd inning, Jermaine Dye hit his 300th career home run. The next batter, Paul Konerko, hit his 300th career home run. It is the first time in MLB history to have such a back-to-back milestone home runs, and the Sox wins it 10–6. On April 25 against the Toronto Blue Jays, Alexei Ramírez hit a grand slam as the Sox won 10–2. The White Sox finished April 11–10.
May
On May 7 against the Detroit Tigers, Mark Buehrle pitched a no-hitter through seventh inning before Plácido Polanco hit a line-drive double to left field; however the Sox shut out the Tigers 6–0. On May 11 against the Cleveland Indians in Progressive Field, Carlos Quentin hit a slump after suffering from plantar fasciitis which hampered his swing. He was forced to miss two games as a result of the injury. On May 15–18, Sox played with Toronto Blue Jays and Sox lost all four games in Toronto for two straight years and lost 10 straight games in Toronto since June 1, 2007. On May 21 against the Minnesota Twins, the Sox had a biggest loss 20–1 since May 10, 2002, when Sox lost to Anaheim Angels 19–0 in Los Angeles. On May 24 against the Pittsburgh Pirates, in the top of the ninth inning, Jack Wilson hit his first home run of season and tied the game at 3. The next batter Nyjer Morgan hit a double and then Delwyn Young singled and Morgan scored from second and Sox trailed it 4–3. In the bottom of the ninth inning, all batters that Matt Capps faced struck out swinging. The next day in Los Angeles against the Angels, the Sox scored 17 runs in one game, the most runs since the 2006 season. Also on that day, Carlos Quentin suffered his heel injury after he hit a double and he was placed on the 15-day disabled list. The last three games of that month, Sox swept the Royals in Kansas City. The White Sox finished May 13–15.
June
On June 1–4 against the Oakland Athletics, the Sox won the first game and lost last three, even though Oakland A's had one of the worst records in the American League, although that team is in a 7-game winning streak. On June 9 against the Detroit Tigers in the bottom of the ninth inning, bases loaded, trailing 6–4, Paul Konerko doubled down the left field line in which Scott Podsednik and Alexei Ramírez scored, but DeWayne Wise was called out at home plate even though replays showed that he looked safe since Wise's hand touched the home plate before he got tagged. The next batter, rookie Gordon Beckham struck out swinging with man on second to end the inning. In the top of the tenth inning, Miguel Cabrera hit a solo home run for a shameful loss 7–6. The Sox finished 12-game 11-day home stand with a bad record 4–8. On June 14 in Milwaukee against the Brewers, Mark Buehrle hit a solo home run in third inning. The Sox defeated the Brewers 5–4. On June 16, it was scheduled that Sox should have played with Cubs in Wrigley Field, but it was postponed due to rain, and the make-up date is announced to be September 3. On June 19 against the Reds in Cincinnati, the Sox had a first loss to Reds since 1999 and the Sox finished the record with Reds in this decade 11–1. The next day with Reds, after the third inning, Sox trailed it 5–0 and Sox came back and win it 10–8, which is the biggest come back so far this season. On June 24 against the Los Angeles Dodgers, Sox hit 6 home runs in one game, first time since June 8, 2004 against the Philadelphia Phillies. The homers are ones by Jermaine Dye, Paul Konerko, Jayson Nix, Alexei Ramírez, and two by Josh Fields. The Sox beat the Dodgers 10–7. In next day, the Sox defeated the Dodgers 6–5 for thirteen innings after Scott Podsednik hit a bases-loaded single and Beckham scored. The Sox took 2-out-of-3 in this series against the Dodgers, even though Dodgers had the best record of baseball. On June 27 against the Cubs, this game went back and forth. Finally, Gordon Beckham hit a walk-off RBI in the bottom of the ninth inning and Josh Fields scored to give Sox an 8–7 victory. The White Sox finished June 15–13.
On August 10 the White Sox claimed Alex Ríos of the Toronto Blue Jays off waivers. Ríos is signed through 2014 for $69.35 million with a no-trade clause this year and a partial no-trade clause through the rest of his contract. On August 12 against the Seattle Mariners in Safeco Field, the score was 0–0 until Ken Griffey Jr. (former White Sox teammate) hit a walk-off single down the right field line in the fourteenth inning with men on first and second in which Adrián Beltré scored. On August 18, Freddy García picked up his first start for the White Sox since September 29, 2006. García get his loss to Kansas City Royals 5–4. On August 24 against the Boston Red Sox in third inning, José Contreras committed an error while trying to pick up a ball down the first baseline by David Ortiz to assist for a final out, which led to a season high six unearned runs and the Sox loses 12–8. On August 31 after the game, the Sox traded away Jim Thome to Los Angeles Dodgers for minor league infielder Justin Fuller and José Contreras to Colorado Rockies for minor league pitcher Brandon Hynick. The White Sox finished August 11–17.
September
On September 2 against the Minnesota Twins at the Metrodome, the Sox trailed 2–0 before Gordon Beckham and Paul Konerko hit back-to-back home runs with 2 outs in the ninth inning when both had 3–2 accounts off of Joe Nathan. Alexei Ramírez hit an RBI single and DeWayne Wise scores, and then Carlos Quentin scored on a wild pitch to Alex Ríos, which makes it 4–2 White Sox and a huge comeback victory to avoid sweep by Twins. On September 3, the interleague game against the Cubs at Wrigley Field was made-up from June 16. The Sox shutout the Cubs 5–0, finishing this year's interleague play 12–6 for Sox and 6–9 for Cubs, both are identical to last season's interleague play. The White Sox starting pitcher Carlos Torres picked up his first major league victory after he was debuted on July 22. On September 4, the White Sox got 20 hits against the Red Sox, the most hits in a game against that team since 1960. On September 5 against the Boston Red Sox, Gavin Floyd retired the first 17 hitters (broken up by Nick Green's single with 2 outs in the 6th inning) and a career-high 11 strikeouts for 8 innings pitched, which the Sox took the victory 5–1. On September 7, Mark Buehrle picked up his first win since the perfect game on July 23. On the next day against the Oakland Athletics, Carlos Torres pitched for just two-thirds of an inning as he allowed 5 runs on 4 hits with 2 homers. It is the shortest outing by a Sox starter in more than six years. Typically, Sox lost to Oakland 11–3. On September 12 at Los Angeles Angels, Scott Podsednik hit an inside-the-park home run, first time for the Sox since Joe Borchard hit that on September 9, 2002, at Kansas City Royals. Typically, Sox defeated the Angels 4–3 in ten innings. On September 17 against the Mariners in Safeco, with the score 3–1 Sox lead in the bottom of the ninth inning, Bobby Jenks allowed two home runs, one by José Lopez with nobody out and one by Bill Hall with two outs, which made it 3–3. In the bottom of the fourteenth inning, Ichiro Suzuki hit a walk-off single to center field with men on first and second in which Ryan Langerhans scored. On September 19, Jake Peavy got his first start for the White Sox since he started for San Diego Padres on June 8. Peavy picked up his first victory over the Royals 13–3. On September 21–23 against the Minnesota Twins, the Sox got swept at home for a first time since August 2007 when they were swept by Red Sox. On September 26 against the Detroit Tigers after 4th inning, Sox led 5–0, Tigers came back and defeated the White Sox 12–5. With that first loss at home on Saturday this season, the Sox finished the season's home games on Saturdays 11–1. The White Sox finished September 13–14.
October
The White Sox finished October 2–1 after winning two-out-of-three games in a series against the Detroit Tigers in Comerica Park.
Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts; BAA = Batting average against