4-Nitromethamphetamine

4-Nitromethamphetamine
Clinical data
Pronunciation/ˌfɔːr naɪtroʊmɛθəmˈfɛtəmiːn/
Other names4-NO2-MA; PNMA; 4-Nitromethylamphetamine; N-Me-PNA; V-61; 4-Nitro-N-methylamphetamine
Drug classCentral nervous system stimulant; Serotonergic agent; Monoaminergic neurotoxin
ATC code
  • none
Identifiers
  • N-methyl-1-(4-nitrophenyl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H14N2O2
Molar mass194.234 g·mol−1
3D model (JSmol)
  • CC(CC1=CC=C(C=C1)[N+](=O)[O-])NC
  • InChI=1S/C10H14N2O2/c1-8(11-2)7-9-3-5-10(6-4-9)12(13)14/h3-6,8,11H,7H2,1-2H3
  • Key:FMYSLOHXMJLTRT-UHFFFAOYSA-N

4-Nitromethamphetamine (4-NO2-MA or PNMA), also known as 4-nitromethylamphetamine, N-Me-PNA, or by the code name V-61, is a central nervous system stimulant that exhibits characteristics of a monoaminergic neurotoxin; it can also be considered a serotonergic agent in studies on rats; at high doses, it depleted catecholamines and led to death.[1][2][3]

See also

References

  1. ^ Leonard, B. E.; Shallice, S. A. (1971). "Effect of p-nitromethylamphetamine on biogenic amines and their amino-acid precursors in rat brain". British Journal of Pharmacology. 43 (4): 732–738. doi:10.1111/j.1476-5381.1971.tb07208.x. ISSN 0007-1188. PMC 1665720. PMID 5152025.
  2. ^ Leonard, B. E. (1972). "Some effects of the hallucinogenic drug 2,5-dimethoxy-4-methylamphetamine on the metabolism of biogenic amines in the rat brain". British Journal of Pharmacology. 45 (1): 165P–166P. ISSN 0007-1188. PMC 1666216. PMID 5041482.
  3. ^ Leonard, B. E. (1972-05-01). "Effect of four amphetamines on brain biogenic amines and their metabolites". Biochemical Pharmacology. 21 (9): 1289–1297. doi:10.1016/0006-2952(72)90290-0. ISSN 0006-2952. PMID 5038674.
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