Few people live along the shores of the gulf, but there are a few towns and communities, including Sachs Harbour, Ulukhaktok, and Paulatuk. Heading north in the gulf one would find the Prince of Wales Strait. Heading southeast and east, the gulf leads through the Dolphin and Union Strait, past Simpson Bay and into the Coronation Gulf. From there one would go through the Dease Strait and into the Queen Maud Gulf, and eventually head northeast into the Victoria Strait. Heading west and northwest a traveller would first enter the Beaufort Sea and then the Arctic Ocean.
The entire gulf is in the Arctictundraclimate region, characterized by extremely cold winters. In late winter the Amundsen Gulf is covered in sea ice. Most of the ice breaks up in July during a normal year, with some areas in the far eastern and northern part of the gulf only breaking up in August.
