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In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently...

In chemistry, dimerization is the process of joining two identical or similar molecular entities by bonds. The resulting bonds can be either strong or...

Pirenzepine has been investigated for use in myopia control. It promotes the homodimerization or oligomerisation of M1 receptors. AFDX-384 Telenzepine Stolerman...

activation results from heterodimerization with another ERBB member or by homodimerization when HER2 concentration are high, for instance in cancer. Amplification...

AP20187 is a ligand that can induce homodimerization of fusion proteins containing the F36V mutant of an FKBP domain(FKBPF36V), available commercially...

homodimers formed either by cross-display or by a disulfide-linked homodimerization mechanism, it is proposed that such HMW aggregates survive on the cell...

enzyme (Figure 3). There are two distinct active sites formed by the homodimerization of ornithine decarboxylase. The size of the opening to the active site...

Domain (TRFH; InterPro: IPR013867) is an area that helps to promote homodimerization of TERF2 with itself. This results in the formation of a quaternary...

mitotic arrest and cell death. Trastuzumab binding to HER2 prevents homodimerization or heterodimerization (HER2/HER3) of the receptor, ultimately inhibiting...

the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein...

(TMD). The TMD is essential for targeting BNIP3 to the mitochondria, homodimerization, and pro-apoptotic function. Its deletion results in the inability...

3-monooxygenase activator activity enzyme binding mRNA binding protein homodimerization activity scaffold protein binding small protein activating enzyme binding...

alpha-D-glucosyltransferase activity manganese ion binding protein homodimerization activity Cellular component cytosol lysosomal lumen extracellular exosome...

binding protein binding protein heterodimerization activity protein homodimerization activity protein transmembrane transporter activity Cellular component...

(April 1997). "A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members". The Journal of Biological Chemistry. 272...

polymerase II cis-regulatory region sequence-specific DNA binding protein homodimerization activity DNA-binding transcription factor activity, RNA polymerase...

neurodegenerative disorders. When NGF binds to the TrkA receptor, it drives the homodimerization of the receptor, which in turn causes the autophosphorylation of the...

reference expression data Gene ontology Molecular function protein homodimerization activity hormone activity peptide hormone receptor binding signaling...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding identical protein binding enzyme binding double-stranded...

BioGPS n/a Gene ontology Molecular function chaperone binding protein homodimerization activity collagen binding protein N-terminus binding immunoglobulin...

Nakagawa T, Yasukawa K, Yamanishi K, et al. (Jun 1993). "IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase". Science....

binding growth factor activity protein binding cytokine activity protein homodimerization activity Cellular component extracellular region extracellular exosome...

DNA binding TFIID-class transcription factor complex binding protein homodimerization activity ADP binding ATPase binding Cellular component membrane nuclear...

data Gene ontology Molecular function transferase activity protein homodimerization activity 3-oxoacid CoA-transferase activity CoA-transferase activity...

407-713) that provide a surface for homodimerization. The autophosphorylation of serine 172, which requires homodimerization and ubiquitinylation of lysines...

protein binding hydrolase activity metallopeptidase activity protein homodimerization activity metalloendopeptidase activity zinc ion binding Cellular component...

activity protein kinase binding protein domain specific binding protein homodimerization activity Cellular component extracellular exosome nucleus cytoplasm...

dimerization: use of a common beta-sheet interface for hetero- and homodimerization". J. Mol. Biol. 353 (3): 664–77. doi:10.1016/j.jmb.2005.08.043. PMID 16181639...

the cytoskeleton, recent work indicates that β-catenin regulates the homodimerization of alpha-catenin, which in turn controls actin branching and bundling...

activity nucleotide binding glycogen phosphorylase activity protein homodimerization activity vitamin binding glycosyltransferase activity 1,4-alpha-oligoglucan...

binding growth factor activity signaling receptor binding protein homodimerization activity identical protein binding Cellular component cytoplasm extracellular...

ion binding cadherin binding transition metal ion binding protein homodimerization activity Cellular component plasma membrane cell projection extracellular...

activation of several cellular processes. When HGF binds c-MET, the receptor homodimerizes and self-phosphorylates to form an SH2 recognition domain. The downstream...

binding oxidoreductase activity superoxide dismutase activity protein homodimerization activity zinc ion binding protein binding copper ion binding protein...

acyltransferase activity peptide alpha-N-acetyltransferase activity protein homodimerization activity N-acetyltransferase activity Cellular component Golgi membrane...

BioGPS n/a Gene ontology Molecular function nucleotide binding protein homodimerization activity ligase activity catalytic activity enzyme binding ATP binding...

function SUMO binding cobalt ion binding metal ion binding protein homodimerization activity zinc ion binding protein binding SMAD binding DNA binding...

protease binding cysteine-type endopeptidase inhibitor activity protein homodimerization activity Cellular component cytoplasm extracellular region extracellular...

the binding of the protein, facilitation in the activity of protein homodimerization, the binding of DNA and facilitation in the activity of protein heterodimerization...

activity catalytic activity isomerase activity ATP binding protein homodimerization activity purine nucleotide binding N-acylglucosamine 2-epimerase activity...

involved in phenylalanine hydroxylation. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1). Mutations...

ligand aldosterone, results in its translocation to the cell nucleus, homodimerization and binding to hormone response elements present in the promoter of...

localization signal is primarily encoded in the hinge region of the AR gene. Homodimerization occurs. Dimerization is mediated by the second (nearest the 3' end)...

activity nucleic acid binding protein binding mRNA binding protein homodimerization activity identical protein binding RNA binding mRNA 3'-UTR binding...

activity phospholipid binding cholesterol transfer activity protein homodimerization activity amyloid-beta binding protein binding tau protein binding metal...

characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle". Human...

activity small molecule binding protease binding iron ion binding protein homodimerization activity enterobactin binding Cellular component extracellular exosome...

binding type I transforming growth factor beta receptor binding protein homodimerization activity transmembrane transporter binding Cellular component cytoplasm...

reference expression data Gene ontology Molecular function protein homodimerization activity potassium channel regulator activity dopamine neurotransmitter...

function palmitoyl-CoA hydrolase activity fatty-acyl-CoA binding protein homodimerization activity carboxylic ester hydrolase activity long-chain fatty acyl-CoA...

expression data Gene ontology Molecular function antigen binding protein homodimerization activity phosphatidylcholine binding immunoglobulin receptor binding...

transporter activity heme transmembrane transporter activity protein homodimerization activity transporter activity ATPase activity protein binding ATP binding...

this protein has a chromo shadow-domain (CSD) that is responsible for homodimerizing, as well as interacting with a variety of chromatin-associated, non-histone...

PMID 12865409. Gerke P, Huber TB, Sellin L, Benzing T, Walz G (April 2003). "Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin...

transcription repressor activity, RNA polymerase II-specific protein homodimerization activity DNA-binding transcription factor activity, RNA polymerase...

transmembrane signaling receptor activity virus receptor activity protein homodimerization activity zinc ion binding extracellular matrix structural constituent...

ATPase-coupled transmembrane transporter activity nucleotide binding protein homodimerization activity transporter activity ATPase activity protein binding identical...

Gene ontology Molecular function peptidase inhibitor activity protein homodimerization activity protease binding protein binding serine-type endopeptidase...

protein kinase binding glyoxylate reductase (NADP+) activity protein homodimerization activity protein-containing complex binding transcription corepressor...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding growth factor activity signaling receptor...

"Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38"...

binding chromo shadow domain binding identical protein binding protein homodimerization activity kinase binding transcription coactivator activity DNA binding...

differentiated (Figure 3). SCF binding to c-KIT causes the receptor to homodimerize and auto-phosphorylate at tyrosine residues. The activation of c-Kit...

expression data Gene ontology Molecular function PDZ domain binding protein homodimerization activity protein binding signaling receptor binding cell adhesion molecule...

"Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38"...

ontology Molecular function protein dimerization activity protein homodimerization activity endopeptidase activity protease binding integrin binding peptidase...

matrix structural constituent signaling receptor activity protein homodimerization activity cell adhesion molecule binding Cellular component extracellular...

allows for is in the association with membrane microdomains, transient homodimerization or in apical sorting in polarized cells. Gerald Karp (2009). Cell and...

pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP)...

activity phosphatidylinositol binding identical protein binding protein homodimerization activity sequence-specific DNA binding chaperone binding histone-dependent...

signaling receptor binding cytokine activity sialic acid binding protein homodimerization activity protein binding identical protein binding extracellular matrix...

"Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38"...

Molecular function signaling receptor binding protein binding protein homodimerization activity cell adhesion molecule binding identical protein binding Cellular...

Krieger JW, Komáromi I, Tóth K, Vámosi G (November 2015). "Evidence for homodimerization of the c-Fos transcription factor in live cells revealed by fluorescence...

transrepression, described below. A direct mechanism of action involves homodimerization of the receptor, translocation via active transport into the nucleus...

1997.0896. PMID 9096235. Chadwick MP, Westley BR, May FE (1997). "Homodimerization and hetero-oligomerization of the single-domain trefoil protein pNR-2/pS2...

ontology Molecular function structural constituent of eye lens protein homodimerization activity protein binding unfolded protein binding chaperone binding...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity zinc ion binding metal ion binding fatty acid binding formaldehyde...

Molecular function calcium ion binding S100 protein binding protein homodimerization activity zinc ion binding metal ion binding calcium-dependent protein...

BioGPS n/a Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component extracellular...

mechanisms, as decoys prevent both the ligand binding and the MET receptor homodimerization. CGEN241 (Compugen) is a decoy MET that is highly efficient in inhibiting...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding RNA binding GTPase binding tRNA binding cytokine...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding protein dimerization activity proteinase activated...

promoter-specific chromatin binding histone deacetylase regulator activity protein homodimerization activity MDM2/MDM4 family protein binding Cellular component cytoplasm...

beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins". J. Biol. Chem. 270...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity GTPase activator activity protein heterodimerization activity...

reference expression data Gene ontology Molecular function protein homodimerization activity metal ion binding single-stranded DNA binding exodeoxyribonuclease...

PMID 1680551. Rajini B, Graham C, Wistow G, Sharma Y (Apr 2003). "Stability, homodimerization, and calcium-binding properties of a single, variant betagamma-crystallin...

protein binding metal ion transmembrane transporter activity protein homodimerization activity zinc ion transmembrane transporter activity Cellular component...

ligase activity proline-tRNA ligase activity zinc ion binding protein homodimerization activity metal ion binding identical protein binding Cellular component...

activity aryldialkylphosphatase activity hydrolase activity protein homodimerization activity metal ion binding acyl-L-homoserine-lactone lactonohydrolase...

cysteines of the NPP1 somatomedin B-like domain have been shown to mediate homodimerization. As shown in the following schematic representation below the SMB domain...

regulation of protein homooligomerization positive regulation of protein homodimerization activity protein ubiquitination proteasome-mediated ubiquitin-dependent...

peptidase activity hydrolase activity virus receptor activity protein homodimerization activity serine-type peptidase activity protease binding aminopeptidase...

binding protein C-terminus binding GTPase regulator activity protein homodimerization activity Cellular component lysosomal membrane Golgi-associated vesicle...

II-specific transcription corepressor activity protein binding protein homodimerization activity transcription cis-regulatory region binding protein heterodimerization...

reference expression data Gene ontology Molecular function protein homodimerization activity hormone activity heme binding enzyme binding Cellular component...

due to safety concerns. (a) NRF2 and KEAP1 protein domains; (b) KEAP1 homodimerizes through the BTB domain, and through the Kelch domains KEAP1 interacts...

telomere maintenance via telomerase positive regulation of protein homodimerization activity negative regulation of protein sumoylation positive regulation...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding RNA polymerase binding identical protein binding...

Molecular function chemokine receptor binding cytokine activity protein homodimerization activity chemokine activity CCR chemokine receptor binding protein...

kinase activity sulfate adenylyltransferase (ATP) activity protein homodimerization activity adenylylsulfate kinase activity Cellular component cytosol...

expression data Gene ontology Molecular function DNA binding protein homodimerization activity transcription corepressor activity calcium-dependent protein...

reference expression data Gene ontology Molecular function protein homodimerization activity flavin adenine dinucleotide binding electron transfer activity...

positive regulation of protein ubiquitination regulation of protein homodimerization activity positive regulation of type I interferon production MyD88-independent...

transporter activity cholesterol binding phosphatidylcholine binding protein homodimerization activity chaperone binding cargo receptor activity Cellular component...

Molecular function protein-macromolecule adaptor activity protein homodimerization activity Toll-like receptor 2 binding Toll-like receptor 4 binding...

activity exo-alpha-sialidase activity beta-galactosidase activity protein homodimerization activity Cellular component perinuclear region of cytoplasm Golgi apparatus...

reference expression data Gene ontology Molecular function protein homodimerization activity signaling receptor complex adaptor activity clathrin binding...

delay and autism spectrum disorder. These mutations disrupt BCL11A homodimerization and transcriptional regulation. BCL11A has also been identified as...

of 135 amino acids at its N-terminus, which is predicted to mediate homodimerization and be involved in cullin 3 binding. At its C-terminus, the protein...

BioGPS n/a Gene ontology Molecular function GPI anchor binding protein homodimerization activity identical protein binding Cellular component anchored component...

Molecular function cocaine binding nitric-oxide synthase binding protein homodimerization activity myosin binding syntaxin-1 binding metal ion binding neurotransmitter:sodium...

kinase activity protein binding identical protein binding protein homodimerization activity Cellular component cytoplasm intracellular anatomical structure...

transferase activity enzyme binding glutathione transferase activity protein homodimerization activity glutathione binding identical protein binding protein binding...

ontology Molecular function phospholipid scramblase activity protein homodimerization activity protein dimerization activity chloride channel activity voltage-gated...

receptor binding hormone activity apelin receptor binding protein homodimerization activity Cellular component perinuclear region of cytoplasm extracellular...

G. D.; Hilton, D. J.; Yoshimura, Y.; Lodish, H. F. (1992-03-15). "Homodimerization and constitutive activation of the erythropoietin receptor". Proceedings...

enhancer sequence-specific binding transcription factor binding protein homodimerization activity protein heterodimerization activity Cellular component nucleus...

reference expression data Gene ontology Molecular function protein homodimerization activity aminoacylase activity peroxidase activity metal ion binding...

reference expression data Gene ontology Molecular function protein homodimerization activity histone deacetylase binding protein binding mRNA binding hydrolase...

Molecular function DNA binding sequence-specific DNA binding protein homodimerization activity DNA-binding transcription factor activity metal ion binding...

glycine binding glycine dehydrogenase (decarboxylating) activity protein homodimerization activity pyridoxal binding enzyme binding Cellular component mitochondrial...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity acyltransferase activity, transferring groups other than amino-acyl...

activator activity involved in apoptotic process protein binding protein homodimerization activity NACHT domain binding CARD domain binding identical protein...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding identical protein binding lipid binding cadherin...

reference expression data Gene ontology Molecular function protein homodimerization activity interleukin-6 receptor binding BMP receptor binding protein...

acting on the CH-OH group of donors, NAD or NADP as acceptor protein homodimerization activity hydroxymethylglutaryl-CoA reductase (NADPH) activity protein...

reference expression data Gene ontology Molecular function protein homodimerization activity protein-containing complex binding transcription factor binding...

expression data Gene ontology Molecular function POZ domain binding protein homodimerization activity ubiquitin protein ligase activity ubiquitin-protein transferase...

activity metallopeptidase activity phosphatidylserine binding protein homodimerization activity oligopeptidase activity cardiolipin binding Cellular component...

data Gene ontology Molecular function oxidoreductase activity protein homodimerization activity NADPH binding quinone binding NADPH:quinone reductase activity...

Molecular function calcium ion binding apolipoprotein binding protein homodimerization activity scaffold protein binding receptor tyrosine kinase binding...

receptor protein tyrosine kinase activity kinase activity protein homodimerization activity ATP binding protein phosphatase binding macrophage colony-stimulating...

Gene ontology Molecular function phospholipase D activity protein homodimerization activity heme oxygenase (decyclizing) activity metal ion binding signal...

860 bp End 79,800,107 bp Gene ontology Molecular function protein homodimerization activity cytidine deaminase activity protein binding catalytic activity...

acid binding ATP binding ATP adenylyltransferase activity protein homodimerization activity transferase activity identical protein binding Cellular component...

Gene ontology Molecular function pyridoxal phosphate binding protein homodimerization activity lyase activity L-threonine ammonia-lyase activity L-serine...

PMID 12865409. Gerke P, Huber TB, Sellin L, Benzing T, Walz G (Apr 2003). "Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin...

ion binding metal ion binding cytoskeletal protein binding protein homodimerization activity cadherin binding Cellular component integral component of...

Molecular function calcium ion binding S100 protein binding protein homodimerization activity ATPase binding calcium-dependent protein binding metal ion...

reference expression data Gene ontology Molecular function protein homodimerization activity channel activity protein binding BH3 domain binding chaperone...

alpha-N-acetylgalactosaminidase activity hydrolase activity protein homodimerization activity alpha-galactosidase activity catalytic activity hydrolase...

analysis of Qk1: a lethal point mutation in mouse quaking prevents homodimerization". Mol. Cell. Biol. 18 (8): 4863–71. doi:10.1128/MCB.18.8.4863. PMC 109071...

expression data Gene ontology Molecular function protein binding protein homodimerization activity disordered domain specific binding identical protein binding...

reference expression data Gene ontology Molecular function protein homodimerization activity metal ion binding monooxygenase activity protein binding protein...

spanning protein tyrosine kinase activity transferase activity protein homodimerization activity protein binding nucleotide binding signal transducer activity...

protein-arginine deiminase activity calcium ion binding arginine binding protein homodimerization activity Cellular component nucleoplasm nucleus cytosol cytoplasm protein-containing...

expression data Gene ontology Molecular function nucleotide binding protein homodimerization activity GTP binding protein binding GTPase activity identical protein...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity hormone activity Cellular component extracellular region extracellular...

activity hydrolase activity, hydrolyzing O-glycosyl compounds protein homodimerization activity hydrolase activity, acting on glycosyl bonds beta-N-acetylhexosaminidase...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity GTPase activator activity signal transducer activity protein...

reference expression data Gene ontology Molecular function protein homodimerization activity mRNA 3'-UTR binding protein binding RNA binding nucleic acid...

expression data Gene ontology Molecular function nucleotide binding protein homodimerization activity protein binding peptidoglycan binding identical protein binding...

function structural constituent of muscle protein binding protein homodimerization activity identical protein binding actin filament binding muscle alpha-actinin...

Molecular function DNA binding sequence-specific DNA binding protein homodimerization activity DNA-binding transcription activator activity, RNA polymerase...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding Cellular component integral component of membrane...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity metal ion binding protein binding dynein light intermediate...

reference expression data Gene ontology Molecular function protein homodimerization activity ion channel activity protein binding calcium channel activity...

function hydrolase activity, hydrolyzing O-glycosyl compounds protein homodimerization activity hydrolase activity, acting on glycosyl bonds raffinose alpha-galactosidase...

constituent of nuclear pore heat shock protein binding mRNA binding protein homodimerization activity chromatin binding protein binding dynein complex binding protein-membrane...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding Cellular component cytoplasm ESCRT III complex...

phospholipase activator activity chemokine receptor binding protein homodimerization activity chemokine receptor antagonist activity protein binding chemoattractant...

ontology Molecular function protein binding channel activity protein homodimerization activity protein heterodimerization activity BH domain binding Cellular...

capabilities, studies speculate that this heterodimer competes with homodimerization of α-catenin.12 To date, there are three α-catenins, in mammals, that...

BioGPS n/a Gene ontology Molecular function calcium ion binding protein homodimerization activity metal ion binding protein heterodimerization activity Cellular...

ontology Molecular function nucleotide binding DNA binding protein homodimerization activity mismatched DNA binding dinucleotide insertion or deletion...

activity calcium ion binding nucleotide diphosphatase activity protein homodimerization activity insulin receptor binding zinc ion binding polysaccharide binding...

activity beta2-adrenergic receptor activity enzyme binding protein homodimerization activity potassium channel regulator activity protein binding G protein-coupled...

identical protein binding hydrolase activity protein binding protein homodimerization activity Cellular component integral component of membrane membrane...

Fab´ antibody FR104, or an octapeptide AB103, which prevents CD28 homodimerization. CD28 has been shown to interact with: GRAP2, Grb2, and PIK3R1. List...

activity phospholipase A2 inhibitor activity metal ion binding protein homodimerization activity single-stranded DNA binding protein binding calcium-dependent...

n/a Gene ontology Molecular function transferase activity protein homodimerization activity acyltransferase activity, transferring groups other than amino-acyl...

protein binding transmembrane signaling receptor activity protein homodimerization activity identical protein binding Cellular component integral component...

region binding protein binding nucleic acid binding DNA binding protein homodimerization activity RNA binding DNA-binding transcription factor activity, RNA...

Molecular function DNA binding sequence-specific DNA binding protein homodimerization activity ubiquitin protein ligase activity histone binding zinc ion...

protein domain specific binding sequence-specific DNA binding protein homodimerization activity RNA binding nuclear receptor activity AF-2 domain binding...

hydrolase activity GTPase activity identical protein binding protein homodimerization activity Cellular component cytoplasm Golgi membrane Golgi apparatus...

transcription activator activity, RNA polymerase II-specific protein homodimerization activity protein heterodimerization activity DNA-binding transcription...

associated with the signalling pathway of JAK1 and JAK2, leading to the homodimerization of STAT1 molecule. It is the common pathway for enhancing expression...

regulation of myeloid cell differentiation positive regulation of protein homodimerization activity positive regulation of protein localization to plasma membrane...

Molecular function transferase activity calcium ion binding protein homodimerization activity isomerase activity metal ion binding prostaglandin-D synthase...

binding IgE binding transmembrane signaling receptor activity protein homodimerization activity Cellular component integral component of membrane membrane...

reference expression data Gene ontology Molecular function protein homodimerization activity ubiquitin protein ligase activity zinc ion binding chromatin...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein binding protein heterodimerization activity DNA binding...

activity beta-galactoside alpha-2,6-sialyltransferase activity protein homodimerization activity Cellular component integral component of membrane Golgi apparatus...

protein binding identical protein binding protein kinase binding protein homodimerization activity protein heterodimerization activity Cellular component cytoplasm...

of three functional domains: (1) an N-terminal domain that mediates homodimerization, suppression of the kinase activity in the absence of cGMP, and interactions...

function DNA binding double-stranded RNA binding protein binding protein homodimerization activity cadherin binding RNA polymerase II cis-regulatory region sequence-specific...

protein kinase activity metal ion binding transferase activity protein homodimerization activity protease binding protein binding protein tyrosine kinase activity...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity metal ion binding aryldialkylphosphatase activity arylesterase...

"Structural Investigation of Human Prolactin Receptor Transmembrane Domain Homodimerization in a Membrane Environment through Multiscale Simulations". The Journal...

transcription factor activity chromatin binding protein binding protein homodimerization activity E-box binding sequence-specific double-stranded DNA binding...

histone acetyltransferase binding metal ion binding DNA binding protein homodimerization activity DNA-binding transcription factor activity, RNA polymerase...

hydrolase activity magnesium ion binding toxic substance binding protein homodimerization activity epoxide hydrolase activity Cellular component extracellular...

expression data Gene ontology Molecular function iron ion binding protein homodimerization activity xanthine oxidase activity flavin adenine dinucleotide binding...

activity retinoic acid binding hexosyltransferase activity protein homodimerization activity glycosyltransferase activity steroid binding protein heterodimerization...

methyltransferase activity transferase activity DNA binding protein homodimerization activity minor groove of adenine-thymine-rich DNA binding DNA-binding...

guanyl-nucleotide exchange factor activity zinc ion binding protein homodimerization activity ubiquitin protein ligase activity Cellular component membrane...

"A cysteine residue in helixII of the bHLH domain is essential for homodimerization of the yeast transcription factor Pho4p". Nucleic Acids Research. 26...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity growth factor binding peptide hormone binding protein binding...

activity beta-galactosidase activity phospholipid binding protein homodimerization activity ganglioside GM1 binding ganglioside GM2 binding ganglioside...

activity double-stranded RNA binding protein binding heme binding protein homodimerization activity metal ion binding RNA binding identical protein binding Cellular...

Soykan T, Tuffy LP, Hammer M, Varoqueaux F, Brose N (September 2012). "Homodimerization and isoform-specific heterodimerization of neuroligins". The Biochemical...

protein binding protein C-terminus binding enzyme binding protein homodimerization activity protein N-terminus binding LEM domain binding identical protein...

reference expression data Gene ontology Molecular function protein homodimerization activity Cellular component cis-Golgi network Golgi cisterna membrane...

Hsp90 protein binding protein-macromolecule adaptor activity protein homodimerization activity misfolded protein binding ubiquitin protein ligase activity...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity phosphatidylcholine binding zinc ion binding phosphatidylserine...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding identical protein binding protein heterodimerization...

protein phosphatase 2A binding channel inhibitor activity protein homodimerization activity channel activity protease binding protein binding sequence-specific...

activity, thioredoxin disulfide as acceptor ferric iron binding protein homodimerization activity Cellular component cytoplasm cytosol ribonucleoside-diphosphate...

coactivator binding telomerase RNA binding telomerase activity protein homodimerization activity chaperone binding template-free RNA nucleotidyltransferase...

ontology Molecular function cytokine activity protein binding protein homodimerization activity cytokine binding cytokine receptor binding Cellular component...

Domanski P, Yan H, Witte MM, Krolewski J, Colamonici OR (1995). "Homodimerization and intermolecular tyrosine phosphorylation of the Tyk-2 tyrosine kinase"...

spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization". Human Molecular Genetics. 15 (23): 3411–9. doi:10.1093/hmg/ddl417...

transferase activity identical protein binding glutathione binding protein homodimerization activity glutathione peroxidase activity protein binding glutathione...

adenosine deaminase activity heparin binding hydrolase activity protein homodimerization activity metal ion binding proteoglycan binding growth factor activity...

expression data Gene ontology Molecular function metal ion binding protein homodimerization activity kinase binding RNA binding protein heterodimerization activity...

expression data Gene ontology Molecular function protein binding protein homodimerization activity Cellular component cytoplasm perinuclear region of cytoplasm...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity acetylcholine binding acetylcholine-gated cation-selective...

kinase activity platelet-derived growth factor receptor binding protein homodimerization activity unfolded protein binding Cellular component AIP1-IRE1 complex...

aminopeptidase activity hydrolase activity metallopeptidase activity protein homodimerization activity manganese ion binding metal ion binding metalloaminopeptidase...

binding identical protein binding cytoskeletal protein binding protein homodimerization activity Cellular component apical junction complex trans-Golgi network...

ontology Molecular function ribosomal large subunit binding protein homodimerization activity ribosomal small subunit binding unfolded protein binding transcription...

binding macrophage colony-stimulating factor receptor binding protein homodimerization activity growth factor activity cytokine activity identical protein...

"Fourteen residues of the U1 snRNP-specific U1A protein are required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation". Molecular...

respectively) are closely packed against each other, mediates the homodimerization of endoglin by forming an intermolecular disulfide bond that involves...

the autophosphorylation and subsequent conformational change of the homodimerized receptor. This conformational change activates the dormant kinase of...

data Gene ontology Molecular function apolipoprotein binding protein homodimerization activity virus receptor activity transporter activity high-density...

DNA 5'-3' exodeoxyribonuclease activity exonuclease activity protein homodimerization activity hydrolase activity single-stranded DNA 3'-5' exodeoxyribonuclease...

prostaglandin E receptor activity NAD+ binding oxidoreductase activity protein homodimerization activity Cellular component nucleoplasm basolateral plasma membrane...

reference expression data Gene ontology Molecular function protein homodimerization activity collagen binding myosin binding protein binding Cellular component...

protein kinase activity kinase binding transferase activity protein homodimerization activity protein binding nucleotide binding nerve growth factor binding...

also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression...

phosphatase activity phosphatase activity hydrolase activity protein homodimerization activity phosphatidylinositol-3-phosphatase activity phosphatidylinositol-3...

reference expression data Gene ontology Molecular function protein homodimerization activity aspartic-type endopeptidase activity peptidase activity protein...

reference expression data Gene ontology Molecular function protein homodimerization activity Cellular component extracellular region desmosome cell-cell...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein binding Cellular component integral component of membrane...

Molecular function identical protein binding protein binding protein homodimerization activity Cellular component cytoplasm ruffle cytosol cell projection...

adrenergic receptor binding G protein-coupled receptor activity protein homodimerization activity epinephrine binding norepinephrine binding alpha-1B adrenergic...

Molecular function protein binding phosphatidylcholine binding protein homodimerization activity ubiquitin-specific protease binding identical protein binding...

transferase activity kynurenine-oxoglutarate transaminase activity protein homodimerization activity L-glutamine:pyruvate aminotransferase activity transaminase...

dikinase activity GTP binding protein binding ATP binding protein homodimerization activity identical protein binding protein heterodimerization activity...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein binding cytokine binding Cellular component extracellular...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity identical protein binding antiporter activity calcium:cation...

function metal ion binding protein domain specific binding protein homodimerization activity DNA binding protein binding damaged DNA binding Cellular component...

transferase activity 4-aminobutyrate transaminase activity protein homodimerization activity transaminase activity iron-sulfur cluster binding metal ion...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity cell-cell adhesion mediator activity Cellular component integral...

binding heme binding enzyme binding oxidoreductase activity protein homodimerization activity dioxygenase activity protein binding peroxidase activity...

activity nucleotidyltransferase activity catalytic activity protein homodimerization activity lipid binding choline-phosphate cytidylyltransferase activity...

MH (May 1998). "Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation". Cell. 93 (4): 605–615. doi:10.1016/S0092-8674(00)81189-7...

Domanski P, Yan H, Witte MM, Krolewski J, Colamonici OR (November 1995). "Homodimerization and intermolecular tyrosine phosphorylation of the Tyk-2 tyrosine kinase"...

expression data Gene ontology Molecular function collagen binding protein homodimerization activity platelet-derived growth factor receptor binding protein binding...

reference expression data Gene ontology Molecular function protein homodimerization activity microtubule binding unfolded protein binding metal ion binding...

nucleotide binding ligase activity protein binding ATP binding protein homodimerization activity metal ion binding Cellular component cytoplasm cytosol Biological...

function nucleotide binding protein dimerization activity protein homodimerization activity ADP binding phospholipid transporter activity ABC-type sterol...

brain-derived neurotrophic factor binding transferase activity protein homodimerization activity protein tyrosine kinase activity nucleotide binding brain-derived...

binding dynactin binding protein-containing complex binding protein homodimerization activity protein binding dynein intermediate chain binding microtubule...

expression data Gene ontology Molecular function chaperone binding protein homodimerization activity protein disulfide isomerase activity protein binding Cellular...

reference expression data Gene ontology Molecular function protein homodimerization activity peroxidase activity thioredoxin peroxidase activity antioxidant...

group of donors aldehyde oxidase activity iron ion binding protein homodimerization activity molybdopterin cofactor binding flavin adenine dinucleotide...

binding glycosyltransferase activity manganese ion binding protein homodimerization activity metal ion binding Cellular component integral component of...

enzyme binding glutathione transferase activity protein binding protein homodimerization activity glutathione binding Cellular component cytoplasm cytosol intercellular...

Molecular function mitochondrial ribosome binding protein binding protein homodimerization activity membrane insertase activity Cellular component integral component...

Molecular function lipase inhibitor activity phospholipase binding protein homodimerization activity lipoprotein lipase activator activity phospholipase activator...

Jiang G, Nepomuceno L, Hopkins K, Sladek FM (Sep 1995). "Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass...

BioGPS n/a Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component integral...

ontology Molecular function nucleic acid binding protein binding protein homodimerization activity RNA binding poly(U) RNA binding single-stranded RNA binding...

characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle". Human...

ontology Molecular function protein binding cadherin binding protein homodimerization activity Cellular component integral component of membrane plasma membrane...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding identical protein binding protein C-terminus...

transcription by RNA polymerase II positive regulation of protein homodimerization activity transcription, DNA-templated positive regulation of cell differentiation...

transferase activity protein kinase activity nucleotide binding protein homodimerization activity vascular endothelial growth factor binding platelet-derived...

expression data Gene ontology Molecular function spectrin binding protein homodimerization activity structural molecule activity calmodulin binding actin filament...

nucleotide binding protein tyrosine phosphatase activator activity protein homodimerization activity isomerase activity peptidyl-prolyl cis-trans isomerase activity...

Molecular function nucleotide binding cyclic-di-GMP binding protein homodimerization activity transcription factor binding protein binding identical protein...

metal ion binding copper ion binding monooxygenase activity protein homodimerization activity oxidoreductase activity protein heterodimerization activity...

binding identical protein binding cytoskeletal protein binding protein homodimerization activity cadherin binding Cellular component cytoplasm integral component...

BioGPS n/a Gene ontology Molecular function oxygen binding protein homodimerization activity cystathionine beta-synthase activity metal ion binding nitric...

activity glutathione transferase activity protein binding protein homodimerization activity identical protein binding Cellular component cytoplasm cytosol...

binding ATP-dependent activity, acting on DNA zinc ion binding protein homodimerization activity metal ion binding Cellular component PML body nuclear matrix...

ENO3 (ENO-β). Each isoform is a protein subunit that can hetero- or homodimerize to form αα, αβ, αγ, ββ, and γγ dimers. The ENO1 gene spans 18 kb and...

pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP)...

transferase activity protein kinase activity nucleotide binding protein homodimerization activity metal ion binding kinase activity protein binding ATP binding...

expression data Gene ontology Molecular function iron ion binding protein homodimerization activity dioxygenase activity metal ion binding histone H3-methyl-arginine-2...

Gene ontology Molecular function potassium channel activity protein homodimerization activity scaffold protein binding voltage-gated potassium channel activity...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity protein binding transporter activity cobalamin binding metal...

ontology Molecular function calcium ion binding heparin binding protein homodimerization activity GTPase inhibitor activity laminin-1 binding protein binding...

binding phosphatidylserine binding phosphatidylinositol binding protein homodimerization activity protein-containing complex binding beta-tubulin binding Cellular...

n/a Gene ontology Molecular function magnesium ion binding protein homodimerization activity oxidoreductase activity, acting on the CH-OH group of donors...

Gene ontology Molecular function retinoid X receptor binding protein homodimerization activity sequence-specific DNA binding beta-catenin binding DNA-binding...

reference expression data Gene ontology Molecular function protein homodimerization activity integrin binding protein binding protein heterodimerization...

nucleotide binding ATPase activity protein binding ATP binding protein homodimerization activity long-chain fatty acid transporter activity Cellular component...

activity carbohydrate phosphatase activity carbohydrate binding protein homodimerization activity protein dimerization activity glycogen binding polysaccharide...

methyltransferase activity transferase activity nucleotide binding protein homodimerization activity folic acid binding thymidylate synthase activity mRNA binding...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity aspartic-type endopeptidase activity aspartic endopeptidase...

attachment to microtubules, whereas the central coiled coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to...

catalytic activity lyase activity pyridoxal phosphate binding protein homodimerization activity kynurenine-glyoxylate transaminase activity transferase activity...

involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene...

other nitrogenous compounds as donors chloride ion binding protein homodimerization activity FAD binding melatonin binding resveratrol binding NAD(P)H...

spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization". Human Molecular Genetics. 15 (23): 3411–9. doi:10.1093/hmg/ddl417...

dephosphorylated. Second, two Ets1 can be activated If two Ets molecules homodimerize. The homodimerization occurs if DNA binding sites are present in the correct orientation...

binding signaling receptor binding cytoskeletal protein binding protein homodimerization activity cadherin binding vascular endothelial growth factor receptor...

reference expression data Gene ontology Molecular function protein homodimerization activity oxidoreductase activity succinate-semialdehyde dehydrogenase...

reference expression data Gene ontology Molecular function protein homodimerization activity protein domain specific binding protein phosphatase 1 binding...

serve as a site for interactions with other proteins and hetero- or homodimerization with other family members. Helios is said to repress interleukin-2...

reference expression data Gene ontology Molecular function protein homodimerization activity G-quadruplex RNA binding mRNA 3'-UTR binding protein binding...

expression data Gene ontology Molecular function protein binding protein homodimerization activity Cellular component integral component of membrane platelet...

Molecular function methyltransferase activity transferase activity protein homodimerization activity zinc ion binding histone methyltransferase activity (H3-K4...

expression data Gene ontology Molecular function nucleotide binding protein homodimerization activity GTP binding phosphoprotein binding protein binding GTPase...

binding magnesium ion binding GTPase activity GTP binding protein homodimerization activity molecular adaptor activity Cellular component cytoplasm cell...

conserved across species. Bves exists as a homodimer in vivo, and homodimerization has been shown to be important for function. Bves is expressed in muscle...

endopeptidase activity hydrolase activity protein binding protein homodimerization activity Cellular component immunological synapse extracellular region...

acid binding tRNA binding RNA binding poly(U) RNA binding protein homodimerization activity sequence-specific mRNA binding Cellular component nucleus...

receptor activity 1-phosphatidylinositol-3-kinase activity protein homodimerization activity unmethylated CpG binding pattern recognition receptor activity...

nuclease activity exonuclease activity hydrolase activity protein homodimerization activity protein-containing complex binding Cellular component cytoplasm...

reference expression data Gene ontology Molecular function protein homodimerization activity signal transducer activity Wnt-protein binding protein heterodimerization...

ion binding DNA binding nucleic acid binding heme binding protein homodimerization activity DNA-binding transcription factor activity, RNA polymerase...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein binding GTPase activator activity identical protein...

transcriptional complex necessary for a productive T-cell response. Instead, NFAT homodimerizes, functioning as a transcriptional factor that induces anergy in the...

spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization". Human Molecular Genetics. 15 (23): 3411–9. doi:10.1093/hmg/ddl417...

transferase activity nucleotide binding protein kinase activity protein homodimerization activity metal ion binding protein serine/threonine kinase activity...

reference expression data Gene ontology Molecular function protein homodimerization activity lactose binding signal transducer activity laminin binding...

data Gene ontology Molecular function beta-catenin binding protein homodimerization activity I-SMAD binding GTPase activator activity protein binding enzyme...

reference expression data Gene ontology Molecular function protein homodimerization activity 6,7-dihydropteridine reductase activity NADPH binding NADH...

pathway cellular response to antibiotic negative regulation of protein homodimerization activity proteolysis involved in cellular protein catabolic process...

activity protein binding GTP binding identical protein binding protein homodimerization activity Cellular component mitochondrial matrix mitochondrion intracellular...

center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization". The Journal of Biological Chemistry. 286 (28): 25056–64. doi:10.1074/jbc...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity GTP binding calcium-dependent protein binding cholesterol...

more favorable RNA binding. Additionally, its N-terminus mediates homodimerization. The second-largest CstF subunit is CSTF2 (also referred to as CstF-64)...

enzyme binding peroxisome matrix targeting signal-2 binding protein homodimerization activity Cellular component cytoplasm peroxisome peroxisomal matrix...

BioGPS n/a Gene ontology Molecular function protein binding protein homodimerization activity Cellular component Golgi lumen extracellular region extracellular...

signaling receptor binding ubiquitin protein ligase binding protein homodimerization activity protein heterodimerization activity BH domain binding Cellular...

signaling receptor activity protein heterodimerization activity protein homodimerization activity Cellular component integral component of membrane alpha-beta...

reference expression data Gene ontology Molecular function protein homodimerization activity protein-membrane adaptor activity chloride transmembrane transporter...

BioGPS n/a Gene ontology Molecular function hydrolase activity protein homodimerization activity Inorganic pyrophosphatase magnesium ion binding metal ion...

kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically...

function G protein-coupled receptor activity epinephrine binding protein homodimerization activity signal transducer activity adrenergic receptor activity protein...

function transferase activity nucleotide binding ATP binding protein homodimerization activity kinase activity NAD+ kinase activity Cellular component mitochondrion...

transcription factor activity DNA binding protein binding protein homodimerization activity transcription corepressor activity metal ion binding protein...

domain binding kainate selective glutamate receptor activity protein homodimerization activity ion channel activity ionotropic glutamate receptor activity...

negative regulation of transcription, DNA-templated regulation of protein homodimerization activity neurotransmitter receptor metabolic process positive regulation...

expression data Gene ontology Molecular function nucleotide binding protein homodimerization activity ATPase activity protein C-terminus binding protein binding...

function lysophosphatidic acid binding calcium ion binding protein homodimerization activity cysteine-type endopeptidase inhibitor activity involved in...

kinase activity IkappaB kinase activity nucleotide binding protein homodimerization activity scaffold protein binding kinase activity protein serine/threonine...

reference expression data Gene ontology Molecular function protein homodimerization activity guanyl-nucleotide exchange factor activity protein serine/threonine...

lipoprotein particle receptor activity apolipoprotein binding protein homodimerization activity kinase inhibitor activity frizzled binding Wnt-protein binding...

Gene ontology Molecular function heat shock protein binding protein homodimerization activity protein N-terminus binding histone binding p53 binding protein...

function cytokine activity interleukin-23 receptor binding protein homodimerization activity interleukin-12 receptor binding protein binding identical...

expression data Gene ontology Molecular function protein binding protein homodimerization activity Cellular component integral component of membrane endoplasmic...

transcription regulatory region sequence-specific DNA binding protein homodimerization activity protein dimerization activity DNA-binding transcription factor...

transcription regulatory region sequence-specific DNA binding protein homodimerization activity transcription corepressor activity DNA-binding transcription...

reference expression data Gene ontology Molecular function protein homodimerization activity aspartic-type endopeptidase activity peptidase activity protein...

intestinal apolipoprotein B is altered. RNA editing by APOBEC-1 requires homodimerization and this complex interacts with RNA-binding proteins to form the editosome...

activity G protein-coupled receptor activity amino acid binding protein homodimerization activity metal ion binding magnesium ion binding calcium ion binding...

transcription factor activity, RNA polymerase II-specific protein homodimerization activity protein heterodimerization activity Cellular component nucleus...

ontology Molecular function sequence-specific DNA binding protein homodimerization activity DNA-binding transcription factor activity zinc ion binding...

Molecular function protein C-terminus binding calcium ion binding protein homodimerization activity protein binding integrin binding extracellular matrix constituent...

activity ATP binding protein kinase activity transferase activity protein homodimerization activity protein binding nucleotide binding identical protein binding...

serine-type peptidase activity protein binding hydrolase activity protein homodimerization activity calcium-dependent protein binding metal ion binding serine-type...

binding sites for Z-band proteins, and 2 Ig domains are the site of homodimerization for myotilin. By contrast, the N-terminal part of myotilin is unique...

reference expression data Gene ontology Molecular function protein homodimerization activity Arp2/3 complex binding 1-phosphatidylinositol binding protein...

transcription factor activity, RNA polymerase II-specific protein homodimerization activity sequence-specific double-stranded DNA binding Cellular component...

ontology Molecular function catalytic activity protein binding protein homodimerization activity cadherin binding Cellular component perinuclear region of...

function protein binding metal ion binding carbohydrate binding protein homodimerization activity asialoglycoprotein receptor activity Cellular component integral...

3-epimerase activity catalytic activity isomerase activity protein homodimerization activity metal ion binding identical protein binding Cellular component...

expression data Gene ontology Molecular function DNA binding protein homodimerization activity transcription corepressor activity LIM domain binding chromatin...

binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding protein heterodimerization...

maleylacetoacetate isomerase activity isomerase activity catalytic activity protein homodimerization activity protein binding identical protein binding hydrolase activity...

reference expression data Gene ontology Molecular function protein homodimerization activity GTPase regulator activity protein binding GTPase activity...

function oxidoreductase activity hormone binding protein binding protein homodimerization activity transcription corepressor activity NADP binding thyroid hormone...

expression data Gene ontology Molecular function spectrin binding protein homodimerization activity transcription factor binding structural molecule activity...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding signaling receptor binding signaling receptor...

ontology Molecular function enzyme binding glutathione binding protein homodimerization activity transferase activity glutathione transferase activity Cellular...

enzyme binding transforming growth factor beta receptor binding protein homodimerization activity collagen binding zinc ion binding chromatin binding cis-regulatory...

reference expression data Gene ontology Molecular function protein homodimerization activity protein N-terminus binding structural molecule activity protein...

positive regulation of JNK cascade positive regulation of protein homodimerization activity respiratory gaseous exchange by respiratory system multicellular...

expression data Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity RNA binding catalytic...

IRF3 and IRF7, as well as DDX3X. This activity allows subsequent homodimerization and nuclear translocation of the IRF3 leading to transcriptional activation...

Gene ontology Molecular function signaling receptor binding protein homodimerization activity cell adhesion molecule binding Cellular component integral...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity aldehyde dehydrogenase [NAD(P)+ activity] NAD+ binding oxidoreductase...

ontology Molecular function DNA binding nucleotide binding protein homodimerization activity mismatched DNA binding dinucleotide insertion or deletion...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity metal ion binding hydrolase activity magnesium ion binding...

procaspase-9 through interactions between CARD domains, followed by homodimerization or heterodimerization. These interactions ensure that apoptosis proceeds...

Gene ontology Molecular function signaling receptor binding protein homodimerization activity cell adhesion molecule binding protein binding identical protein...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein domain specific binding protein binding CARD domain...

expression data Gene ontology Molecular function nucleotide binding protein homodimerization activity virus receptor activity peptide binding zinc ion binding amyloid-beta...

ontology Molecular function calcium ion binding protein binding protein homodimerization activity metal ion binding RNA binding Cellular component cytosol plasma...

reference expression data Gene ontology Molecular function protein homodimerization activity receptor tyrosine kinase binding zinc ion binding SH2 domain...

ontology Molecular function coproporphyrinogen oxidase activity protein homodimerization activity structural constituent of eye lens identical protein binding...

reference expression data Gene ontology Molecular function protein homodimerization activity poly(U) RNA binding ribosome binding poly(G) binding protein...

Molecular function DNA binding protein dimerization activity protein homodimerization activity DNA-binding transcription factor activity HMG box domain binding...

function zinc ion binding chaperone binding protein binding protein homodimerization activity metal ion binding transporter activity Cellular component...

reference expression data Gene ontology Molecular function protein homodimerization activity protein N-terminus binding transcription factor binding protein...

binding type I transforming growth factor beta receptor binding protein homodimerization activity protein serine/threonine kinase activator activity protein...

Molecular function DNA binding protein dimerization activity protein homodimerization activity MRF binding transcription corepressor activity histone deacetylase...

GP, Avruch J (February 2002). "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene...

BioGPS n/a Gene ontology Molecular function catalytic activity protein homodimerization activity lyase activity 4-hydroxy-2-oxoglutarate aldolase activity...

expression data Gene ontology Molecular function DNA binding protein homodimerization activity DNA-binding transcription factor activity RNA polymerase II...

sequence-specific DNA binding serine-tRNA ligase activity protein binding protein homodimerization activity DNA binding RNA polymerase II cis-regulatory region sequence-specific...

mid-region of desmoplakin, a coiled-coil rod domain is responsible for homodimerization. Desmosomes are intercellular junctions that tightly link adjacent...

cysteine residue in the helix-loop-helix domain of Id2 is critical for homodimerization and function". Biochemical and Biophysical Research Communications...

reference expression data Gene ontology Molecular function protein homodimerization activity catalytic activity carboxylic acid binding amino acid binding...

Molecular function protein binding protein kinase binding protein homodimerization activity identical protein binding Cellular component membrane endosome...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein heterodimerization activity cell adhesion molecule...

carbohydrates account for about 12% of the molecular mass (55-58 kDa). Homodimerization is required before LPL can be secreted from cells. After secretion...

light intermediate chain binding cytoskeletal protein binding protein homodimerization activity protein heterodimerization activity scaffold protein binding...

ontology Molecular function protein binding caspase binding protein homodimerization activity protein heterodimerization activity Cellular component nucleus...

reference expression data Gene ontology Molecular function protein homodimerization activity insulin receptor binding leptin receptor binding epidermal...

protein binding cobalamin binding identical protein binding protein homodimerization activity Cellular component mitochondrial matrix mitochondrion Biological...

polymerase II distal enhancer sequence-specific binding RNA binding protein homodimerization activity protein heterodimerization activity ubiquitin protein ligase...

nucleotide binding ligase activity protein binding ATP binding protein homodimerization activity threonine-tRNA ligase activity tRNA binding RNA binding Cellular...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity protein domain specific binding protein binding epidermal...

data Gene ontology Molecular function calcium ion binding protein homodimerization activity quinone binding aliphatic-amine oxidase activity metal ion...

Molecular function ciliary neurotrophic factor receptor activity protein homodimerization activity interleukin-6 receptor binding protein binding cytokine receptor...

function zinc ion binding chaperone binding protein binding protein homodimerization activity metal ion binding transporter activity Cellular component...

hydroxypyruvate reductase activity glyoxylate reductase (NADP+) activity protein homodimerization activity Cellular component cytoplasm transcription regulator complex...

oxidoreductase activity NAD-retinol dehydrogenase activity protein homodimerization activity androsterone dehydrogenase activity androstan-3-alpha,17-beta-diol...

contains five tandem ankyrin repeats. Studies have shown that CARP can homodimerize. Studies have also shown that CARP is N-terminally, post-translationally...

Molecular function iron-sulfur cluster binding protein binding protein homodimerization activity metal ion binding 2 iron, 2 sulfur cluster binding RNA binding...

ontology Molecular function protein binding cholesterol binding protein homodimerization activity Cellular component lysosomal membrane membrane integral component...

binding ubiquitin protein ligase binding protein kinase binding protein homodimerization activity Cellular component endosome membrane cytoplasm mitochondrial...

anti-parallel beta-strands. These structures are hypothesized to mediate the homodimerization by interaction of alpha/beta structures. These structural studies also...

ontology Molecular function protein binding kinase binding protein homodimerization activity protein phosphatase binding protein tyrosine kinase binding...

repressor activity, RNA polymerase II-specific N-box binding protein homodimerization activity DNA binding DNA-binding transcription factor activity, RNA...

binding sequence-specific DNA binding chromatin DNA binding protein homodimerization activity identical protein binding DNA-binding transcription factor...

activity iron ion binding tRNA binding oxidoreductase activity protein homodimerization activity dioxygenase activity metal ion binding tRNAPhe...

transmembrane signaling receptor activity carbohydrate binding protein homodimerization activity Cellular component integral component of membrane integral...

activity protein binding chloride ion binding peptide binding protein homodimerization activity peptide hormone binding Cellular component integral component...

Cohen-Gonsaud, Martin (2019-02-12). "Structural basis for chemically-induced homodimerization of a single domain antibody". Scientific Reports. 9 (1): 1840. Bibcode:2019NatSR...

expression data Gene ontology Molecular function protein binding protein homodimerization activity identical protein binding ubiquitin-protein transferase activity...

pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP)...

Molecular function nucleotide binding microtubule motor activity protein homodimerization activity microtubule binding ATPase activity protein binding WW domain...

activity 2-aminoadipate transaminase activity catalytic activity protein homodimerization activity transaminase activity Cellular component mitochondrial matrix...

RNP consensus sub-motif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and...

sequence-specific DNA binding protein dimerization activity protein homodimerization activity DNA-binding transcription factor activity chromatin binding...

reference expression data Gene ontology Molecular function protein homodimerization activity actin filament binding protein binding identical protein binding...

reference expression data Gene ontology Molecular function protein homodimerization activity protein domain specific binding signal transducer activity...

BioGPS n/a Gene ontology Molecular function cytokine activity protein homodimerization activity transforming growth factor beta receptor binding growth factor...

nucleotide binding NADHX epimerase activity protein binding protein homodimerization activity isomerase activity metal ion binding NADPHX epimerase activity...

polymerase II cis-regulatory region sequence-specific DNA binding protein homodimerization activity chromatin binding NF-kappaB binding protein binding protein...

reference expression data Gene ontology Molecular function protein homodimerization activity histone binding chromatin binding metal ion binding ubiquitin-protein...

ontology Molecular function peptidase activity hydrolase activity protein homodimerization activity aspartic-type endopeptidase activity Cellular component endosome...

reference expression data Gene ontology Molecular function protein homodimerization activity Cellular component cytoplasm lipid droplet intracellular anatomical...

BioGPS n/a Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component mitochondrial...

expression data Gene ontology Molecular function protein binding protein homodimerization activity protein domain specific binding ubiquitin protein ligase binding...

iron ion binding peptidyl-asparagine 3-dioxygenase activity protein homodimerization activity ankyrin repeat binding zinc ion binding dioxygenase activity...

transferase activity nucleotide binding protein kinase activity protein homodimerization activity kinase activity protein serine/threonine kinase activity protein...

sequence-specific DNA binding DNA-binding transcription factor activity protein homodimerization activity identical protein binding DNA-binding transcription factor...

binding hydrolase activity protein-arginine deiminase activity protein homodimerization activity metal ion binding Cellular component extracellular exosome...

activity G protein-coupled receptor activity epinephrine binding protein homodimerization activity beta3-adrenergic receptor activity norepinephrine binding...

reference expression data Gene ontology Molecular function protein homodimerization activity microtubule binding protein binding beta-tubulin binding protein...

binding identical protein binding cytoskeletal protein binding protein homodimerization activity cadherin binding Cellular component axon terminus integral...

Pfeifer GP, Avruch J (Feb 2002). "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene...

data BioGPS n/a Gene ontology Molecular function DNA binding protein homodimerization activity metal ion binding K63-linked polyubiquitin modification-dependent...

ion binding chromatin binding ATP binding ATPase activity protein homodimerization activity nucleotide binding hydrolase activity Cellular component nucleus...

Molecular function transferase activity nucleotide binding protein homodimerization activity cholinesterase activity signal transducer activity choline...

expression data Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component extracellular...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding Cellular component cytosol membrane proteasome...

neuron differentiation spermatogenesis negative regulation of protein homodimerization activity striated muscle cell differentiation protein homooligomerization...

Gene ontology Molecular function lipase inhibitor activity protein homodimerization activity phosphatidylcholine binding lipid transporter activity apolipoprotein...

cobalamin binding protein binding FAD binding demethylase activity protein homodimerization activity glutathione binding cyanocobalamin reductase (cyanide-eliminating)...

receptor tyrosine kinase binding identical protein binding protein homodimerization activity Cellular component cytoplasm cytosol endosome plasma membrane...

function epidermal growth factor receptor binding protein binding protein homodimerization activity dystroglycan binding Cellular component extracellular region...

reference expression data Gene ontology Molecular function protein homodimerization activity frizzled binding protein binding growth factor activity cytokine...

reference expression data Gene ontology Molecular function protein homodimerization activity identical protein binding protein binding Cellular component...

sequence-specific DNA binding DNA binding protein dimerization activity protein homodimerization activity DNA-binding transcription factor activity bHLH transcription...

Molecular function calcium ion binding S100 protein binding protein homodimerization activity ion transmembrane transporter activity zinc ion binding metal...

BioGPS n/a Gene ontology Molecular function calcium ion binding protein homodimerization activity transporter activity endopeptidase activity phosphatidylserine...

growth factor-activated receptor activity transferase activity protein homodimerization activity protein binding nucleotide binding protein tyrosine kinase...

tyrosine kinase activity protein phosphatase binding ATP binding protein homodimerization activity receptor tyrosine kinase transmembrane signaling receptor...

activity nucleotidyltransferase activity catalytic activity protein homodimerization activity D-ribitol-5-phosphate cytidylyltransferase activity cytidylyltransferase...

expression data BioGPS n/a Gene ontology Molecular function protein homodimerization activity Cellular component Golgi lumen extracellular region azurophil...

element binding DNA binding protein dimerization activity protein homodimerization activity DNA-binding transcription factor activity transcription factor...

activity acetylglucosaminyltransferase activity protein homodimerization activity glycosyltransferase activity N-acetylglucosaminyl-proteoglycan...

binding protein phosphatase binding identical protein binding protein homodimerization activity peptidoglycan binding oligosaccharide binding Cellular component...

Molecular function zinc ion binding p53 binding protein binding protein homodimerization activity metal ion binding ubiquitin-protein transferase activity transferase...

metal ion binding isocitrate dehydrogenase (NADP+) activity protein homodimerization activity Cellular component mitochondrial inner membrane cytosol mitochondrial...

expression data Gene ontology Molecular function protein binding protein homodimerization activity metal ion binding calcium-dependent cysteine-type endopeptidase...

binding cholesterol binding cholesterol transfer activity protein homodimerization activity Cellular component cytoplasm integral component of membrane...

expression data Gene ontology Molecular function protein binding protein homodimerization activity Cellular component cytoplasm perinuclear region of cytoplasm...

reference expression data Gene ontology Molecular function protein homodimerization activity scaffold protein binding carboxylic ester hydrolase activity...

activity retinoic acid binding hexosyltransferase activity protein homodimerization activity glycosyltransferase activity protein heterodimerization activity...

reference expression data Gene ontology Molecular function protein homodimerization activity nucleoside binding cytidine deaminase activity zinc ion binding...

Molecular function DNA binding rRNA binding heparin binding protein homodimerization activity peptide binding protein binding nucleic acid binding nuclease...

reference expression data Gene ontology Molecular function protein homodimerization activity protein binding protein-containing complex binding Cellular...

region of contact surface that is involved in a well-known interaction (homodimerization) between two molecules of 14-3-3ζ protein. Once the photo-methionine...

ubiquitin protein ligase binding methylglyoxal synthase activity protein homodimerization activity lyase activity Cellular component cytosol extracellular exosome...

inositol monophosphate phosphatase activity manganese ion binding protein homodimerization activity metal ion binding lithium ion binding protein binding identical...

transferase activity nucleotide binding protein kinase activity protein homodimerization activity kinase activity protein binding glutamate receptor binding...

binding virus receptor activity cytoskeletal protein binding protein homodimerization activity cadherin binding Cellular component integral component of...

Kim (2017-12-22). "Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies". Journal of Biological Chemistry...

binding protein kinase activity protein binding ATP binding protein homodimerization activity kinetochore binding Cellular component spindle membrane cytoplasm...

expression data Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component extracellular...

binding transferase activity ADP-ribose diphosphatase activity protein homodimerization activity nucleotidyltransferase activity Cellular component cytosol...

Molecular function transferase activity nucleotide binding protein homodimerization activity pyridoxal kinase activity zinc ion binding potassium ion binding...

protein kinase binding protein-containing complex binding protein homodimerization activity microtubule plus-end binding Cellular component cytoplasm...

binding double-stranded RNA binding identical protein binding protein homodimerization activity pre-miRNA binding miRNA binding Cellular component cytoplasm...

protein kinase activity Hsp90 protein binding nucleotide binding protein homodimerization activity kinase activity protein serine/threonine kinase activity protein...

5-formyltetrahydrofolate cyclo-ligase activity enzyme inhibitor activity protein homodimerization activity ATPase binding calmodulin binding ATPase inhibitor activity...