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KPXR-TV (channel 48) is a television station licensed to Cedar Rapids, Iowa, United States, broadcasting the Ion Television network to Eastern Iowa. It is owned and operated by the Ion Media subsidiary of the E. W. Scripps Company, and maintains offices on Blairs Ferry Road Northeast in Cedar Rapids and a transmitter near Walker, Iowa.

The station first signed on the air on May 3, 1997, as KTVC; it was originally an affiliate of the Infomall TV Network (inTV), a service operated by Paxson Communications that specialized in paid programming. On August 31, 1998, KPXR became a charter station of the family-oriented Pax TV network (later reformatted into a general entertainment service as i: Independent Television, now Ion Television), with religious programming from The Worship Network airing during the overnight hours.

On September 24, 2020, the Cincinnati-based E. W. Scripps Company announced it would purchase KPXR-TV's owner, Ion Media, for $2.65 billion, with financing from Berkshire Hathaway.^[2] Part of the deal included divesting 23 stations nationally to Inyo Broadcast Holdings (then-undisclosed at the time of the announcement) that would maintain Ion affiliations.^[3]

The station's signal is multiplexed:

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