Taft Avenue Extension merges with Elpidio Quirino Avenue at the intersection with Redemptorist Road near the Pasay–Parañaque border. This section of R-2 runs the entire length of Parañaque from Baclaran to San Dionisio.
From Alabang–Zapote Road south to Tagaytay, R-2 is known as Aguinaldo Highway. It is the main north-south thoroughfare in the province of Cavite linking Las Piñas, Metro Manila with Cavite, particularly the cities and municipalities of Bacoor, Imus, Dasmariñas, Silang, and Tagaytay. R-2 ends at the Tagaytay Rotunda, providing the famous view of the Taal Lake.