Search Results: Retrotransposition


Transposable element
Jumat, 2026-07-24 03:30:25

DeBerardinis RJ, Kazazian HH (March 1999). "Exon shuffling by L1 retrotransposition". Science. 283 (5407): 1530–4. Bibcode:1999Sci...283.1530M. doi:10...

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Gene duplication
Jumat, 2026-08-14 02:26:28

duplications include ectopic recombination, replication slippage, retrotransposition event, aneuploidy, and polyploidy. Duplications arise from an event...

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Retrotransposon
Selasa, 2026-08-11 19:15:13

retrotransposition affects brain function. LINE retrotransposition is also a feature of several cancers, but it is unclear whether retrotransposition...

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LINE1
Minggu, 2026-05-24 05:26:04

RNA-binding and nucleic acid chaperone activity that are necessary for retrotransposition. The second ORF of L1 encodes a protein that has endonuclease and...

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Long interspersed nuclear element
Sabtu, 2026-07-04 03:14:33

are non functional. It has been shown that host cells regulate L1 retrotransposition activity, for example through epigenetic silencing. For example, the...

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LTR retrotransposon
Sabtu, 2026-07-04 03:37:15

newly created cDNA into another genomic location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that the rate of...

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Pseudogene
Minggu, 2026-08-16 09:36:48

pseudogenes are as follows: In higher eukaryotes, particularly mammals, retrotransposition is a fairly common event that has had a huge impact on the composition...

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Ralph DeBerardinis
Senin, 2026-03-23 09:22:18

DeBerardinis, MD". Retrieved 2022-04-23. DeBerardinis, Ralph John (1998). Retrotransposition and evolution of L1 sequences in mammalian genomes (Thesis). OCLC 187477554...

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Lithospermum erythrorhizon
Senin, 2026-07-20 07:27:15

has been sequenced and has facilitated the discovery of a putative retrotransposition-derived duplication event that produced a 4-hydroxybenzoate geranyltransferase...

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Fusion protein
Jumat, 2026-05-01 06:52:06

mutation, such as a chromosomal translocation, tandem duplication, or retrotransposition creates a novel coding sequence containing parts of the coding sequences...

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Short interspersed nuclear element
Sabtu, 2025-10-04 11:51:09

them remarkably successful at persisting and amplifying (through retrotransposition) within the genomes of eukaryotes. These "parasites" which have become...

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Haig Kazazian
Jumat, 2026-07-31 07:14:33

humans. After this discovery, he focused on basic research into LINE retrotransposition in humans and its implications for disease. Haig Hagop Kazazian Jr...

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Human genome
Senin, 2026-08-10 02:28:19

Moran JV, et al. (April 2003). "Hot L1s account for the bulk of retrotransposition in the human population". Proceedings of the National Academy of Sciences...

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Mosaic (genetics)
Minggu, 2026-08-09 03:42:45

of human life. Somatic mosaics are common in embryogenesis due to retrotransposition of long interspersed nuclear element-1 (LINE-1 or L1) and Alu transposable...

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Molecular evolution
Senin, 2026-06-29 11:36:17

genetic mechanisms including gene duplication, de novo gene birth, retrotransposition, chimeric gene formation, recruitment of non-coding sequence into...

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UnaL2 LINE 3′ element
Jumat, 2019-10-25 21:53:12

stem-loop that is critical for their retrotransposition found in their 3′ end. The first step of retrotransposition is the recognition of their 3′ tails...

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PCBP1
Sabtu, 2025-07-19 13:52:15

PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues...

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Human somatic variation
Senin, 2026-07-27 06:10:37

germline. L1 retrotransposition can happen also in somatic cells causing mosaicism (SLAVs – L1-associated variations) and in cancer. Retrotransposition is a copy...

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Zeus (gene)
Senin, 2022-10-17 18:12:07

especially from D. melanogaster and D. simulans. Zeus arose via a retrotransposition from Caf40, a DNA-binding protein. It differs by 107 amino acid substitutions...

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ZC3HAV1
Selasa, 2026-08-11 19:49:02

antiviral activities, ZAP has been reported to inhibit LINE and Alu retrotransposition. Alternative splicing occurs at this locus and at least four isoform...

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Aicardi–Goutières syndrome
Selasa, 2026-05-19 22:41:43

& Xiao-Fang Yu (Sep 26, 2013). "Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutieres syndrome-related SAMHD1". Cell Reports. 4 (6):...

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Sex chromosome
Selasa, 2026-08-11 19:22:37

the larger size of X than Y-chromosome may be due to duplication or retrotransposition and size of Y remains same. Ferns and lycophytes have bisexual gametophytes...

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G. Steven Bova
Selasa, 2026-08-11 18:06:11

methylation changes, androgen receptor splice variants, mobile element (L1) retrotransposition in cancer, and methods for tissue and data management for molecular...

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Benzo(a)pyrene
Kamis, 2026-08-06 04:10:03

(2006). "Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by Benzo(a)pyrene, a Ubiquitous Environmental Carcinogen". Cancer...

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Non-coding DNA
Selasa, 2026-06-23 09:00:27

2006). "Doubling genome size without polyploidization: dynamics of retrotransposition-driven genomic expansions in Oryza australiensis, a wild relative...

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Knockout rat
Senin, 2026-04-27 17:41:53

mechanism for non-LTR retrotransposition. Cell, 1993. 72(4): p. 595-605. Ostertag, E.M., et al., A mouse model of human L1 retrotransposition. Nat Genet, 2002...

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Restriction enzyme
Sabtu, 2026-06-27 08:04:31

SL, Roy-Engel AM, Deininger PL (June 2008). "ERCC1/XPF limits L1 retrotransposition". DNA Repair. 7 (6): 983–9. doi:10.1016/j.dnarep.2008.02.006. PMC 2483505...

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GM3
Kamis, 2026-07-16 09:26:16

million years ago, a process well-documented in primates and known as retrotransposition-mediated deletion. As a result, modern humans exhibit no traces of...

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Intron
Minggu, 2026-08-16 09:10:17

HR, Liu L, Matsuura M, Lambowitz AM, Perlman PS (November 2001). "Retrotransposition of a yeast group II intron occurs by reverse splicing directly into...

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Group II intron
Selasa, 2026-08-11 18:12:27

conformations Group II introns assume during splicing. The mechanism of retrotransposition by Group II introns have also been revealed through Cryo - Electron...

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Gene family
Sabtu, 2026-02-21 08:49:11

that have lost their function after being moved around the genome by retrotransposition. Pseudogenes that have become isolated from the gene family they originated...

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Homeobox protein NANOG
Kamis, 2025-11-13 20:48:13

promoter sequences and the absence of introns as a result of mRNA retrotransposition all in the same places: one duplication pseudogene and nine retropseudogenes...

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Cer6 (retrotransposon)
Kamis, 2026-07-02 17:54:43

the newly created cDNA into another location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that most LTR-retrotransposons...

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APOBEC3D
Senin, 2026-06-08 02:17:40

(2007). "All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition". Nucleic Acids Research. 35 (9): 2955–2964. doi:10.1093/nar/gkm181...

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R2 RNA element
Minggu, 2025-09-14 21:58:17

by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition". Cell. 72 (4): 595–605. doi:10.1016/0092-8674(93)90078-5. PMID 7679954...

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Shift work sleep disorder
Selasa, 2026-07-07 03:03:32

VA, Hill SM, et al. (July 2014). "Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated...

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Complete Genomics
Selasa, 2026-08-11 14:53:45

1186/1471-2105-13-121. PMC 3403908. PMID 22672699. Bundo M (2014). "Increased L1 retrotransposition in the neuronal genome in schizophrenia". Neuron. 81 (2): 306–313...

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TRIM5alpha
Senin, 2026-04-27 01:29:32

DM, Sokolskaja E, Berthoux L, Luban J (Jul 2004). "Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1". Nature. 430 (6999):...

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Gene amplification
Selasa, 2026-08-11 18:07:33

duplications that lead to gene amplification include ectopic recombination, retrotransposition events, and replication slippage. Broader-scale evolutionary or chromosomal...

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RBMX
Senin, 2026-03-02 14:46:33

found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants...

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60S ribosomal protein L10-like
Jumat, 2025-08-22 16:53:04

Kenmochi N (December 2002). "Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes". Nucleic Acids Research....

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Alysson Muotri
Jumat, 2026-07-10 22:13:37

2005). "Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition". Nature. 435 (7044): 903–910. Bibcode:2005Natur.435..903M. doi:10...

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APOBEC3F
Rabu, 2025-07-16 04:24:00

Stenglein MD, Harris RS (2006). "APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism". J. Biol. Chem. 281 (25):...

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Chemosensory protein
Jumat, 2025-09-12 06:18:15

loss and gain, and retrotransposition events [4, 14, 32, 40-41, 45]. A single unified hypothesis of RNA editing and retrotransposition-driven evolution...

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L1Base
Selasa, 2019-10-22 15:12:37

Mundlos, S; Robinson, PN; Zemojtel, T (4 January 2017). "L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes". Nucleic Acids Research. 45...

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EEF1B2
Kamis, 2025-07-17 23:26:09

elongation factor 1B(alpha) in human and mouse shows EEF1B1 to be a recent retrotransposition event". Genomics. 77 (3): 145–8. doi:10.1006/geno.2001.6626. PMID 11597139...

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Exon shuffling
Sabtu, 2025-11-01 00:40:37

Molecular features suggest that this duplication was mediated by L1 retrotransposition: the derived sequence was flanked by 15bp target side duplications...

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RUNX3
Senin, 2026-03-09 12:29:37

2003). "An important role for RUNX3 in human L1 transcription and retrotransposition". Nucleic Acids Research. 31 (16): 4929–4940. doi:10.1093/nar/gkg663...

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(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide
Kamis, 2026-06-11 00:33:32

(2006). "Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by Benzo[a]pyrene, a Ubiquitous Environmental Carcinogen". Cancer...

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Paulinella
Rabu, 2026-08-12 00:09:45

multiplied many times over through a "copy-paste" mechanism called retrotransposition, enabling them to function more efficiently and making them more tolerant...

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Oryza australiensis
Rabu, 2026-02-25 23:07:05

(2006-10-01). "Doubling genome size without polyploidization: Dynamics of retrotransposition-driven genomic expansions in Oryza australiensis, a wild relative...

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Structural variation
Senin, 2026-08-17 21:35:29

949–51. doi:10.1038/ng1416. PMID 15286789. Lupski, James R. (2010). "Retrotransposition and Structural Variation in the Human Genome". Cell. 141 (7): 1110–2...

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Restriction modification system
Kamis, 2025-11-20 18:39:36

Gasior SL, Roy-Engel AM, Deininger PL (2008). "ERCC1/XPF limits L1 retrotransposition". DNA Repair. 7 (6): 983–989. doi:10.1016/j.dnarep.2008.02.006. PMC 2483505...

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Chimeric gene
Selasa, 2026-01-27 02:05:35

are inadvertently combined. Chimeric genes can also form through retrotransposition where a retrotransposon accidentally copies the transcript of a gene...

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RNA-directed DNA methylation
Minggu, 2026-08-16 13:21:20

Ossowski S, et al. (September 2009). "Selective epigenetic control of retrotransposition in Arabidopsis". Nature. 461 (7262): 427–30. Bibcode:2009Natur.461...

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Sudha Bhattacharya
Kamis, 2026-02-12 09:56:24

ribosomal biogenesis. Her work on retrotransposons confirmed that retrotransposition is observed by means of excessive frequency recombination- which could...

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APOBEC3B
Senin, 2026-08-10 11:22:03

Stenglein MD, Harris RS (2006). "APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism". The Journal of Biological...

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Segmental duplication on the human Y chromosome
Rabu, 2026-02-04 06:50:45

evolution such as base-pair substitutions, insertions, deletions, and retrotransposition are all possible. It has been suggested that segmental duplications...

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Eukaryotic chromosome fine structure
Jumat, 2025-02-21 14:10:06

Retrotransposons are sequences in the DNA that are the result of retrotransposition of RNA. LINEs and SINEs are examples where the sequences are repeats...

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APOBEC3C
Senin, 2026-05-18 10:20:08

GG, Münk C (August 2006). "APOBEC3 proteins inhibit human LINE-1 retrotransposition". The Journal of Biological Chemistry. 281 (31): 22161–72. doi:10...

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Genome evolution
Sabtu, 2026-04-11 07:41:42

can occur as the result of an error in recombination or through a retrotransposition event. Duplicate genes are often immune to the selective pressure...

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