Search Results: Retrotransposition
Redirect to:
Transposable element
Jumat, 2026-07-24 03:30:25DeBerardinis RJ, Kazazian HH (March 1999). "Exon shuffling by L1 retrotransposition". Science. 283 (5407): 1530–4. Bibcode:1999Sci...283.1530M. doi:10...
Click to read more »Gene duplication
Jumat, 2026-08-14 02:26:28duplications include ectopic recombination, replication slippage, retrotransposition event, aneuploidy, and polyploidy. Duplications arise from an event...
Click to read more »Retrotransposon
Selasa, 2026-08-11 19:15:13retrotransposition affects brain function. LINE retrotransposition is also a feature of several cancers, but it is unclear whether retrotransposition...
Click to read more »LINE1
Minggu, 2026-05-24 05:26:04RNA-binding and nucleic acid chaperone activity that are necessary for retrotransposition. The second ORF of L1 encodes a protein that has endonuclease and...
Click to read more »Long interspersed nuclear element
Sabtu, 2026-07-04 03:14:33are non functional. It has been shown that host cells regulate L1 retrotransposition activity, for example through epigenetic silencing. For example, the...
Click to read more »LTR retrotransposon
Sabtu, 2026-07-04 03:37:15newly created cDNA into another genomic location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that the rate of...
Click to read more »Pseudogene
Minggu, 2026-08-16 09:36:48pseudogenes are as follows: In higher eukaryotes, particularly mammals, retrotransposition is a fairly common event that has had a huge impact on the composition...
Click to read more »Ralph DeBerardinis
Senin, 2026-03-23 09:22:18DeBerardinis, MD". Retrieved 2022-04-23. DeBerardinis, Ralph John (1998). Retrotransposition and evolution of L1 sequences in mammalian genomes (Thesis). OCLC 187477554...
Click to read more »Lithospermum erythrorhizon
Senin, 2026-07-20 07:27:15has been sequenced and has facilitated the discovery of a putative retrotransposition-derived duplication event that produced a 4-hydroxybenzoate geranyltransferase...
Click to read more »Fusion protein
Jumat, 2026-05-01 06:52:06mutation, such as a chromosomal translocation, tandem duplication, or retrotransposition creates a novel coding sequence containing parts of the coding sequences...
Click to read more »Short interspersed nuclear element
Sabtu, 2025-10-04 11:51:09them remarkably successful at persisting and amplifying (through retrotransposition) within the genomes of eukaryotes. These "parasites" which have become...
Click to read more »Haig Kazazian
Jumat, 2026-07-31 07:14:33humans. After this discovery, he focused on basic research into LINE retrotransposition in humans and its implications for disease. Haig Hagop Kazazian Jr...
Click to read more »Human genome
Senin, 2026-08-10 02:28:19Moran JV, et al. (April 2003). "Hot L1s account for the bulk of retrotransposition in the human population". Proceedings of the National Academy of Sciences...
Click to read more »Mosaic (genetics)
Minggu, 2026-08-09 03:42:45of human life. Somatic mosaics are common in embryogenesis due to retrotransposition of long interspersed nuclear element-1 (LINE-1 or L1) and Alu transposable...
Click to read more »Molecular evolution
Senin, 2026-06-29 11:36:17genetic mechanisms including gene duplication, de novo gene birth, retrotransposition, chimeric gene formation, recruitment of non-coding sequence into...
Click to read more »UnaL2 LINE 3′ element
Jumat, 2019-10-25 21:53:12stem-loop that is critical for their retrotransposition found in their 3′ end. The first step of retrotransposition is the recognition of their 3′ tails...
Click to read more »PCBP1
Sabtu, 2025-07-19 13:52:15PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues...
Click to read more »Human somatic variation
Senin, 2026-07-27 06:10:37germline. L1 retrotransposition can happen also in somatic cells causing mosaicism (SLAVs – L1-associated variations) and in cancer. Retrotransposition is a copy...
Click to read more »Zeus (gene)
Senin, 2022-10-17 18:12:07especially from D. melanogaster and D. simulans. Zeus arose via a retrotransposition from Caf40, a DNA-binding protein. It differs by 107 amino acid substitutions...
Click to read more »ZC3HAV1
Selasa, 2026-08-11 19:49:02antiviral activities, ZAP has been reported to inhibit LINE and Alu retrotransposition. Alternative splicing occurs at this locus and at least four isoform...
Click to read more »Aicardi–Goutières syndrome
Selasa, 2026-05-19 22:41:43& Xiao-Fang Yu (Sep 26, 2013). "Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutieres syndrome-related SAMHD1". Cell Reports. 4 (6):...
Click to read more »Sex chromosome
Selasa, 2026-08-11 19:22:37the larger size of X than Y-chromosome may be due to duplication or retrotransposition and size of Y remains same. Ferns and lycophytes have bisexual gametophytes...
Click to read more »G. Steven Bova
Selasa, 2026-08-11 18:06:11methylation changes, androgen receptor splice variants, mobile element (L1) retrotransposition in cancer, and methods for tissue and data management for molecular...
Click to read more »Benzo(a)pyrene
Kamis, 2026-08-06 04:10:03(2006). "Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by Benzo(a)pyrene, a Ubiquitous Environmental Carcinogen". Cancer...
Click to read more »Non-coding DNA
Selasa, 2026-06-23 09:00:272006). "Doubling genome size without polyploidization: dynamics of retrotransposition-driven genomic expansions in Oryza australiensis, a wild relative...
Click to read more »Knockout rat
Senin, 2026-04-27 17:41:53mechanism for non-LTR retrotransposition. Cell, 1993. 72(4): p. 595-605. Ostertag, E.M., et al., A mouse model of human L1 retrotransposition. Nat Genet, 2002...
Click to read more »Restriction enzyme
Sabtu, 2026-06-27 08:04:31SL, Roy-Engel AM, Deininger PL (June 2008). "ERCC1/XPF limits L1 retrotransposition". DNA Repair. 7 (6): 983–9. doi:10.1016/j.dnarep.2008.02.006. PMC 2483505...
Click to read more »GM3
Kamis, 2026-07-16 09:26:16million years ago, a process well-documented in primates and known as retrotransposition-mediated deletion. As a result, modern humans exhibit no traces of...
Click to read more »Intron
Minggu, 2026-08-16 09:10:17HR, Liu L, Matsuura M, Lambowitz AM, Perlman PS (November 2001). "Retrotransposition of a yeast group II intron occurs by reverse splicing directly into...
Click to read more »Group II intron
Selasa, 2026-08-11 18:12:27conformations Group II introns assume during splicing. The mechanism of retrotransposition by Group II introns have also been revealed through Cryo - Electron...
Click to read more »Gene family
Sabtu, 2026-02-21 08:49:11that have lost their function after being moved around the genome by retrotransposition. Pseudogenes that have become isolated from the gene family they originated...
Click to read more »Homeobox protein NANOG
Kamis, 2025-11-13 20:48:13promoter sequences and the absence of introns as a result of mRNA retrotransposition all in the same places: one duplication pseudogene and nine retropseudogenes...
Click to read more »Cer6 (retrotransposon)
Kamis, 2026-07-02 17:54:43the newly created cDNA into another location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that most LTR-retrotransposons...
Click to read more »APOBEC3D
Senin, 2026-06-08 02:17:40(2007). "All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition". Nucleic Acids Research. 35 (9): 2955–2964. doi:10.1093/nar/gkm181...
Click to read more »R2 RNA element
Minggu, 2025-09-14 21:58:17by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition". Cell. 72 (4): 595–605. doi:10.1016/0092-8674(93)90078-5. PMID 7679954...
Click to read more »Shift work sleep disorder
Selasa, 2026-07-07 03:03:32VA, Hill SM, et al. (July 2014). "Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated...
Click to read more »Complete Genomics
Selasa, 2026-08-11 14:53:451186/1471-2105-13-121. PMC 3403908. PMID 22672699. Bundo M (2014). "Increased L1 retrotransposition in the neuronal genome in schizophrenia". Neuron. 81 (2): 306–313...
Click to read more »TRIM5alpha
Senin, 2026-04-27 01:29:32DM, Sokolskaja E, Berthoux L, Luban J (Jul 2004). "Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1". Nature. 430 (6999):...
Click to read more »Gene amplification
Selasa, 2026-08-11 18:07:33duplications that lead to gene amplification include ectopic recombination, retrotransposition events, and replication slippage. Broader-scale evolutionary or chromosomal...
Click to read more »RBMX
Senin, 2026-03-02 14:46:33found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants...
Click to read more »60S ribosomal protein L10-like
Jumat, 2025-08-22 16:53:04Kenmochi N (December 2002). "Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes". Nucleic Acids Research....
Click to read more »Alysson Muotri
Jumat, 2026-07-10 22:13:372005). "Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition". Nature. 435 (7044): 903–910. Bibcode:2005Natur.435..903M. doi:10...
Click to read more »APOBEC3F
Rabu, 2025-07-16 04:24:00Stenglein MD, Harris RS (2006). "APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism". J. Biol. Chem. 281 (25):...
Click to read more »Chemosensory protein
Jumat, 2025-09-12 06:18:15loss and gain, and retrotransposition events [4, 14, 32, 40-41, 45]. A single unified hypothesis of RNA editing and retrotransposition-driven evolution...
Click to read more »L1Base
Selasa, 2019-10-22 15:12:37Mundlos, S; Robinson, PN; Zemojtel, T (4 January 2017). "L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes". Nucleic Acids Research. 45...
Click to read more »EEF1B2
Kamis, 2025-07-17 23:26:09elongation factor 1B(alpha) in human and mouse shows EEF1B1 to be a recent retrotransposition event". Genomics. 77 (3): 145–8. doi:10.1006/geno.2001.6626. PMID 11597139...
Click to read more »Exon shuffling
Sabtu, 2025-11-01 00:40:37Molecular features suggest that this duplication was mediated by L1 retrotransposition: the derived sequence was flanked by 15bp target side duplications...
Click to read more »RUNX3
Senin, 2026-03-09 12:29:372003). "An important role for RUNX3 in human L1 transcription and retrotransposition". Nucleic Acids Research. 31 (16): 4929–4940. doi:10.1093/nar/gkg663...
Click to read more »(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide
Kamis, 2026-06-11 00:33:32(2006). "Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by Benzo[a]pyrene, a Ubiquitous Environmental Carcinogen". Cancer...
Click to read more »Paulinella
Rabu, 2026-08-12 00:09:45multiplied many times over through a "copy-paste" mechanism called retrotransposition, enabling them to function more efficiently and making them more tolerant...
Click to read more »Oryza australiensis
Rabu, 2026-02-25 23:07:05(2006-10-01). "Doubling genome size without polyploidization: Dynamics of retrotransposition-driven genomic expansions in Oryza australiensis, a wild relative...
Click to read more »Structural variation
Senin, 2026-08-17 21:35:29949–51. doi:10.1038/ng1416. PMID 15286789. Lupski, James R. (2010). "Retrotransposition and Structural Variation in the Human Genome". Cell. 141 (7): 1110–2...
Click to read more »Restriction modification system
Kamis, 2025-11-20 18:39:36Gasior SL, Roy-Engel AM, Deininger PL (2008). "ERCC1/XPF limits L1 retrotransposition". DNA Repair. 7 (6): 983–989. doi:10.1016/j.dnarep.2008.02.006. PMC 2483505...
Click to read more »Chimeric gene
Selasa, 2026-01-27 02:05:35are inadvertently combined. Chimeric genes can also form through retrotransposition where a retrotransposon accidentally copies the transcript of a gene...
Click to read more »RNA-directed DNA methylation
Minggu, 2026-08-16 13:21:20Ossowski S, et al. (September 2009). "Selective epigenetic control of retrotransposition in Arabidopsis". Nature. 461 (7262): 427–30. Bibcode:2009Natur.461...
Click to read more »Sudha Bhattacharya
Kamis, 2026-02-12 09:56:24ribosomal biogenesis. Her work on retrotransposons confirmed that retrotransposition is observed by means of excessive frequency recombination- which could...
Click to read more »APOBEC3B
Senin, 2026-08-10 11:22:03Stenglein MD, Harris RS (2006). "APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism". The Journal of Biological...
Click to read more »Segmental duplication on the human Y chromosome
Rabu, 2026-02-04 06:50:45evolution such as base-pair substitutions, insertions, deletions, and retrotransposition are all possible. It has been suggested that segmental duplications...
Click to read more »Eukaryotic chromosome fine structure
Jumat, 2025-02-21 14:10:06Retrotransposons are sequences in the DNA that are the result of retrotransposition of RNA. LINEs and SINEs are examples where the sequences are repeats...
Click to read more »APOBEC3C
Senin, 2026-05-18 10:20:08GG, Münk C (August 2006). "APOBEC3 proteins inhibit human LINE-1 retrotransposition". The Journal of Biological Chemistry. 281 (31): 22161–72. doi:10...
Click to read more »Genome evolution
Sabtu, 2026-04-11 07:41:42can occur as the result of an error in recombination or through a retrotransposition event. Duplicate genes are often immune to the selective pressure...
Click to read more »