60S ribosomal protein L24

RPL24
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0
Identifiers
Aliases	RPL24, HEL-S-310, L24, ribosomal protein L24
External IDs	OMIM: 604180; MGI: 1915443; HomoloGene: 763; GeneCards: RPL24; OMA:RPL24 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	101,686,718 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	55,791,798 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; anterior pituitary; ; ganglionic eminence; ; left ovary; ; islet of Langerhans; ; thyroid gland; ; corpus callosum; ; left lobe of thyroid gland; ; cerebellar hemisphere; ; canal of the cervix;
	Top expressed in
	embryo; ; epiblast; ; embryo; ; morula; ; ventricular zone; ; urinary bladder; ; ganglionic eminence; ; uterus; ; blastocyst; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; structural constituent of ribosome; cadherin binding; RNA binding;
Cellular component	cytoplasm; cytosol; ribosome; membrane; cytosolic large ribosomal subunit; extracellular exosome; endoplasmic reticulum; polysomal ribosome; synapse;
Biological process	assembly of large subunit precursor of preribosome; viral transcription; mitotic cell cycle checkpoint signaling; exit from mitosis; SRP-dependent cotranslational protein targeting to membrane; retina development in camera-type eye; ribosomal large subunit assembly; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; optic nerve development; retinal ganglion cell axon guidance; rRNA processing; protein biosynthesis; cytoplasmic translation;
	Sources:Amigo / QuickGO
Orthologs
	6152
	68193
	ENSG00000114391
	ENSMUSG00000098274
	P83731
	Q8BP67
	NM_000986
	NM_024218
	NP_000977
	NP_077180
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal protein L24 is a protein that in humans is encoded by the RPL24 gene.^[5]^[6]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from Saccharomyces cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000114391 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000098274 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
^ ^a ^b "Entrez Gene: RPL24 ribosomal protein L24".

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Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank". Gene. 150 (2): 243–50. doi:10.1016/0378-1119(94)90433-2. PMID 7821789.
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Johnson KR (1993). "Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30". Gene. 123 (2): 283–5. doi:10.1016/0378-1119(93)90139-T. PMID 8428672.
Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics. 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437.
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Odintsova TI, Müller EC, Ivanov AV, et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58. doi:10.1023/A:1025068419698. PMID 12962325. S2CID 10710245.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
Lehner B, Sanderson CM (2004). "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Tu LC, Yan X, Hood L, Lin B (2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells". Mol. Cell. Proteomics. 6 (4): 575–88. doi:10.1074/mcp.M600249-MCP200. PMID 17220478.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000114391 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000098274 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9582194-5] Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.

[entrez-6] "Entrez Gene: RPL24 ribosomal protein L24".

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[5]

[6]

60S ribosomal protein L24

References

Further reading