ZNF274

ZNF274
Identifiers
AliasesZNF274, HFB101, ZF2, ZKSCAN19, ZSCAN51, zinc finger protein 274
External IDsOMIM: 605467; MGI: 2176229; GeneCards: ZNF274
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

10782

170936

Ensembl

ENSG00000171606

ENSMUSG00000021514

UniProt

Q96GC6

Q921B4

RefSeq (mRNA)

NM_001278734
NM_001278735
NM_016324
NM_016325
NM_133502

NM_178364

RefSeq (protein)

NP_001265663
NP_057408
NP_057409
NP_598009

n/a

Location (UCSC)Chr 19: 58.18 – 58.21 MbChr 13: 65.43 – 65.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 274 is a protein that in humans is encoded by the ZNF274 gene.[5][6]

This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171606 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021514 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yano K, Ueki N, Oda T, Seki N, Masuho Y, Muramatsu M (Jun 2000). "Identification and characterization of human ZNF274 cDNA, which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability". Genomics. 65 (1): 75–80. doi:10.1006/geno.2000.6140. PMID 10777669.
  6. ^ a b "Entrez Gene: ZNF274 zinc finger protein 274".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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